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Fibrotic valvular heart disease subsequent to bromocriptine treatment.

Abstract
Ergot alkaloids, such as ergotamine, have been associated with numerous vascular complications and with valvular heart disease. The authors describe a man who developed fibrosis of three heart valves during a 5-year treatment with bromocriptine for Parkinson disease. There were no other plausible causes. To our knowledge, such a side effect has never been described with this drug.
AuthorsJacques Serratrice, Patrick Disdier, Gilbert Habib, François Viallet, Pierre-Jean Weiller
JournalCardiology in review (Cardiol Rev) 2002 Nov-Dec Vol. 10 Issue 6 Pg. 334-6 ISSN: 1061-5377 [Print] United States
PMID12390688 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Bromocriptine
Topics
  • Bromocriptine (adverse effects, therapeutic use)
  • Fibrosis (chemically induced, diagnosis)
  • Heart Valve Diseases (chemically induced, diagnosis)
  • Humans
  • Male
  • Middle Aged
  • Parkinson Disease (drug therapy)

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