Definitive radiation therapy for infiltrative thyroid carcinoma in dogs.

Abstract

The medical records of eight dogs with histopathologically confirmed infiltrative thyroid carcinoma treated with external beam radiation were reviewed and a retrospective analysis of survival and local tumor control were performed. The dogs received a definitive radiotherapy protocol of 46.8-48 Gray. All dogs had a reduction in tumor size to a clinically undetectable level on follow up examinations. Kaplan-Meier analysis indicated a median survival time of 24.5 months. Pulmonary metastasis was detected in three dogs and one of these dogs had concurrent bone metastasis. One dog had bone metastasis alone. Two dogs were alive at the censor. This study suggests that fractionated, definitive radiation therapy using multiple, moderate doses of radiation is an effective treatment for local control of invasive thyroid carcinoma in dogs.

• Authors: L Pack, R E Roberts, S D Dawson, H D Dookwah
• Journal: Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association (Vet Radiol Ultrasound) 2001 Sep-Oct Vol. 42 Issue 5 Pg. 471-4 ISSN: 1058-8183 [Print] England
• PMID: 11678572 (Publication Type: Journal Article)

Topics

• Animals
• Bone Neoplasms (secondary, veterinary)
• Carcinoma (mortality, radiotherapy, secondary, veterinary)
• Dog Diseases (mortality, pathology, radiotherapy)
• Dogs
• Female
• Georgia
• Lung Neoplasms (secondary, veterinary)
• Male
• Radiation Dosage
• Records (veterinary)
• Retrospective Studies
• Survival Analysis
• Thyroid Neoplasms (mortality, pathology, radiotherapy, veterinary)
• Treatment Outcome