| Abstract | A recently described one-day regimen of praziquantel (PZQ) therapy for neurocysticercosis (NCC), three doses of 25 mg/k given at 2 h intervals, was applied in eight patients with viable NCC cysts without any evidence of inflammation. Resolution of lesions in computed tomography (CT) was observed in all five patients with a single cyst, whereas all cysts survived in three patients with multiple brain parasites. One-day praziquantel is a good regimen for patients with a single viable brain cysticercus but is poorly effective for multiple cysts. |
| Authors | E J Pretell, H H García, R H Gilman, H Saavedra, M Martinez, Cysticercosis Working Group in Peru
(Affiliation: Department of Transmissible Diseases, Instituto Nacional de Ciencias Neurológicas, Jr. Ancash 1271, Barrios Altos, 1, Lima, Peru.)
|
| Journal | Clinical neurology and neurosurgery
(Clin Neurol Neurosurg)
Vol. 103
Issue 3
Pg. 175-7
(Oct 2001)
ISSN: 0303-8467 Netherlands |
| PMID | 11532559
(Publication Type: Clinical Trial, Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.)
|
| Chemical References |
- Anthelmintics
- Praziquantel
|
| Topics |
- Adult
- Animals
- Anthelmintics
(therapeutic use)
- Brain Diseases
(drug therapy, radiography)
- Cysticercus
(drug effects)
- Female
- Humans
- Male
- Middle Aged
- Neurocysticercosis
(drug therapy, radiography)
- Praziquantel
(therapeutic use)
- Tomography, X-Ray Computed
- Treatment Failure
- Treatment Outcome
|
