| Abstract | Therapeutic effect of radio-iodine treatment on thyroid patients with autonomously functioning toxic thyroid nodule was evaluated. Fifty one patients were given a standard dose of 10 mci of radioiodine (I-131) and were followed up for 2-3 years. The failure rate (relapse after 10 mci of radioiodine) of this regime was 10%. It was found that the nodules less than or equal to 3 cms. in size were completely cured after a dose of 10 mic. of radio-iodine therapy, over a follow up period of next 6 months. Patients having nodules larger than 3 cms. relapsed after first dose of 10 mci of radio-iodine, but were cured completely after the second dose of 10 mci of radio-iodine therapy. Tri-iodothyronine (T3) and thyroxine (T4) values were both found to be high before giving treatment in all the cases. Only one case developed hypothyroidism after radioiodine therapy. |
| Authors | R Sharma, A Bhatnagar, A Mondal, R Kashyap, C M Khanna
(Affiliation: Inst. of Nuclear Medicine and Allied Sciences, New Delhi.)
|
| Journal | The Journal of the Association of Physicians of India
(J Assoc Physicians India)
Vol. 43
Issue 3
Pg. 167-9, 172
(Mar 1995)
ISSN: 0004-5772 India |
| PMID | 11256900
(Publication Type: Clinical Trial, Journal Article)
|
| Chemical References |
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| Topics |
- Female
- Follow-Up Studies
- Goiter, Nodular
(complications, radiotherapy)
- Humans
- Hyperthyroidism
(etiology, radiotherapy)
- Iodine Radioisotopes
(adverse effects, therapeutic use)
- Male
- Middle Aged
- Recurrence
- Treatment Outcome
|
