Rhegmatogenous retinal detachment in retinoblastoma patients undergoing chemoreduction and cryotherapy.

Abstract

PURPOSE:

To report the development of rhegmatogenous retinal detachment, with the retinal break adjacent to a cryotherapy scar, in three patients undergoing systemic chemotherapy for intraocular retinoblastoma.

METHOD:

Case series.

RESULTS:

Three patients with intraocular retinoblastoma were referred after poor response to systemic chemotherapy and local cryotherapy; three eyes of these three patients were noted to have rhegmatogenous retinal detachment and active retinoblastoma, with retinal breaks adjacent to cryotherapy scars.

CONCLUSION:

Rhegmatogenous retinal detachment may result from retinal necrosis associated with cryotherapy in the setting of intraocular retinoblastoma treated with systemic chemotherapy and local cryotherapy.

• Authors: S R Anagnoste, I U Scott, T G Murray, D Kramer, S Toledano
• Journal: American journal of ophthalmology (Am J Ophthalmol) Vol. 129 Issue 6 Pg. 817-9 (Jun 2000) ISSN: 0002-9394 [Print] United States
• PMID: 10927003 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Antineoplastic Combined Chemotherapy Protocols (adverse effects, therapeutic use)
• Child, Preschool
• Combined Modality Therapy
• Cryotherapy (adverse effects)
• Eye Enucleation
• Female
• Humans
• Infant
• Male
• Retinal Detachment (diagnostic imaging, etiology, surgery)
• Retinal Neoplasms (therapy)
• Retinal Perforations (diagnostic imaging, etiology, surgery)
• Retinoblastoma (therapy)
• Ultrasonography