Abstract | BACKGROUND: METHODS AND RESULTS: Two kidney transplant recipients developed symptomatic anemia requiring blood transfusions. Common causes of anemia, such as gastrointestinal bleeding, iron/ vitamin deficiencies, hemolysis, and drug toxicities, were ruled out. A peripheral smear revealed low reticulocyte count. Bone marrow examination showed hypoplastic bone marrow with intranuclear inclusions suggestive of human Parvovirus. This was confirmed by immunohistochemical analysis. Treatment with i.v. immunoglobulin G resulted in a dramatic sustained response. Transplant kidney function remained stable. CONCLUSION:
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Authors | S Pamidi, K Friedman, B Kampalath, C Eshoa, S Hariharan |
Journal | Transplantation
(Transplantation)
Vol. 69
Issue 12
Pg. 2666-9
(Jun 27 2000)
ISSN: 0041-1337 [Print] United States |
PMID | 10910292
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Immunoglobulin G
- Immunoglobulins, Intravenous
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Topics |
- Adult
- Anemia
(etiology, therapy)
- Female
- Humans
- Immunoglobulin G
(therapeutic use)
- Immunoglobulins, Intravenous
(therapeutic use)
- Immunohistochemistry
- Kidney Transplantation
(adverse effects)
- Male
- Middle Aged
- Parvoviridae Infections
(complications)
- Parvovirus B19, Human
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