HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Blue toe syndrome: treatment with intra-arterial stents and review of therapies.

AbstractPURPOSE:
To determine if intra-arterial stent placement can adequately treat lesions producing microemboli to the lower extremities.
MATERIALS AND METHODS:
During a 6.5-year period, 15 patients presenting with blue toe syndrome had 16 presumed embolic lesions treated with intra-arterial stents. These patients were evaluated during routine clinical follow-up during a 6-month period. This evaluation included physical and noninvasive arterial examinations. When patients could not return for follow-up, hospital, clinical, vascular laboratory, and radiology records were reviewed to assemble the appropriate information. Outcomes included symptoms of recurrent emboli, amputation, and death.
RESULTS:
Treated embolic lesions included two aortic stenoses, three bilateral iliac artery stenoses, nine unilateral iliac artery stenoses (one patient received separate treatment of unilateral iliac lesions), and two superficial femoral artery stenoses. Patients were followed-up for a mean of 18 months. Eight of 15 patients (53%) were improved or stable without complications. There were eight negative outcomes experienced in seven patients. Three patients (20%) were deceased at follow-up. Four patients (27%) had undergone amputation; one transmetatarsal amputation and three below-the-knee amputations. Only one of these was related to progressive disease in the treated extremity (7%). One patient (7%) experienced recurrent embolic symptoms. Stents were patent in all patients.
CONCLUSION:
Patients with blue toe syndrome are at high risk of limb loss and mortality despite treatment. Intra-arterial stent placement provides an alternative to standard surgical treatment. Further studies are needed to define the optimum therapy.
AuthorsW J Matchett, D R McFarland, J F Eidt, M M Moursi
JournalJournal of vascular and interventional radiology : JVIR (J Vasc Interv Radiol) Vol. 11 Issue 5 Pg. 585-92 (May 2000) ISSN: 1051-0443 [Print] United States
PMID10834489 (Publication Type: Journal Article)
Topics
  • Adult
  • Aged
  • Angioplasty, Balloon (methods)
  • Blue Toe Syndrome (therapy)
  • Embolism (prevention & control)
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Radiography, Interventional (methods)
  • Stents

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: