Ultrasonographically guided injection of corticosteroids for the treatment of retroseptal capillary hemangiomas in infants.

Abstract

PURPOSE:

Injection of corticosteroids is a well-documented and successful mode of treatment for periorbital capillary hemangiomas. Because of the greater potential risk involved with retrobulbar injections, no prior study has described this treatment for tumors located behind the orbital septum. Although retroseptal intraorbital capillary hemangiomas comprise only 7% of all adnexal capillary hemangiomas, complications such as optic nerve compression or astigmatism may necessitate treatment.

METHODS:

Three patients with deep orbital hemangiomas that caused vision-threatening complications were treated with intralesional injections of triamcinolone and betamethasone. Orbital injection was performed with use of real-time ultrasonographic guidance of the needle. This technique was valuable in providing continuous, accurate, and safe advancement of the needletip in the orbit to avoid the globe and orbital walls. Ultrasonography also permitted precise placement of the needle tip within the tumor and visualization of the injected material.

RESULTS:

Significant improvement was demonstrated in all cases on the basis of both ultrasonographic measurements and regression of clinical manifestations such as astigmatism, chemosis, proptosis, and optic nerve pallor. No complications were noted.

CONCLUSION:

Intralesional injection of corticosteroids to treat retroseptal and retrobulbar capillary hemangiomas was found to be a safe and effective treatment modality in our patients. Positioning of the injecting needle was guided by ultrasonography.

• Authors: D Neumann, S J Isenberg, A L Rosenbaum, R A Goldberg, V H Jotterand
• Journal: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus (J AAPOS) Vol. 1 Issue 1 Pg. 34-40 (Mar 1997) ISSN: 1091-8531 [Print] United States
• PMID: 10530983 (Publication Type: Case Reports, Journal Article)

Chemical References

• Adrenal Cortex Hormones
• Glucocorticoids
• Triamcinolone
• Betamethasone

Topics

• Adrenal Cortex Hormones (administration & dosage, therapeutic use)
• Astigmatism (etiology)
• Betamethasone (administration & dosage, therapeutic use)
• Conjunctival Diseases (etiology)
• Edema (etiology)
• Exophthalmos (etiology)
• Eye Neoplasms (complications, diagnosis, diagnostic imaging, drug therapy)
• Female
• Glucocorticoids (administration & dosage, therapeutic use)
• Hemangioma, Capillary (complications, diagnosis, diagnostic imaging, drug therapy)
• Humans
• Infant
• Injections
• Magnetic Resonance Imaging
• Optic Nerve Diseases (etiology)
• Treatment Outcome
• Triamcinolone (administration & dosage, therapeutic use)
• Ultrasonography