Case report: a rare association of primary biliary cirrhosis and systemic lupus erythematosus and review of the literature.

Abstract

We report a rare occurrence of systemic lupus erythematosus in a patient known to have had well-documented primary biliary cirrhosis for 10 years. The presentation was dramatic with pericardial tamponade, but responded well to high dose corticosteroid. There are only five such definite associations reported in the literature. In the present case, other possible causes were considered, such as drug-induced cholestasis, drug-induced lupus, autoimmune chronic active hepatitis and the overlap syndrome.

• Authors: S Islam, J W Riordan, J A McDonald
• Journal: Journal of gastroenterology and hepatology (J Gastroenterol Hepatol) Vol. 14 Issue 5 Pg. 431-5 (May 1999) ISSN: 0815-9319 [Print] Australia
• PMID: 10355507 (Publication Type: Case Reports, Journal Article, Review)

Topics

• Biopsy
• Female
• Humans
• Liver (pathology)
• Liver Cirrhosis, Biliary (complications, pathology)
• Lupus Erythematosus, Systemic (complications, pathology)
• Middle Aged