Recurrent mycetoma of the foot.

Abstract

Mycetoma, also known as madura foot, is a local, chronic, slowly progressive disease with the classic presentation involving tumefaction, multiple draining sinuses, and grain-filled pus. It is primarily produced by either a bacteria (actinomycetoma) or a fungal (eumycetoma) organism. Determining the causative organism is fundamental to the treatment process. All types of mycetoma infections should be treated with early surgical debridement and tissue culture. Tissue should be sent for gross, microscopic, and histopathologic evaluation. In addition to surgical management, these patients should be managed adjunctively with a prolonged course of chemotherapy. Patients with actinomycetoma are treated with an antibiotic and can expect to have a clinical cure with little chance for recurrence, whereas, patients with eumycetoma are treated with an antifungal agent and usually do poorly with a high rate of recurrence. The case presented involved an infection due to Actinomadura madurae (Nocardiaform madurae) and demonstrates successful treatment with surgical resection and prolonged doxycycline chemotherapy.

• Authors: J D Davis, P A Stone, J J McGarry
• Journal: The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons (J Foot Ankle Surg) 1999 Jan-Feb Vol. 38 Issue 1 Pg. 55-60 ISSN: 1067-2516 [Print] United States
• PMID: 10028471 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Bacterial Agents
• Doxycycline

Topics

• Actinomycetales
• Adult
• Anti-Bacterial Agents (therapeutic use)
• Debridement
• Diagnosis, Differential
• Doxycycline (therapeutic use)
• Foot Diseases (diagnosis, microbiology, therapy)
• Humans
• Male
• Mycetoma (diagnosis, microbiology, therapy)
• Recurrence