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Dihydrouracil Dehydrogenase (NAD+)

An enzyme that catalyzes the oxidation of 5,6-dihydrouracil to URACIL using NAD as a cofactor. This enzyme also plays a role in the catabolism of the antimetabolite 5-FLUOROURACIL.
Also Known As:
Dihydrothymine Dehydrogenase (NAD); Dihydrouracil Dehydrogenase; Dihydrouracil Dehydrogenase (NAD); Dehydrogenase, Dihydrouracil
Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Ohmiya, Harumi: 1 article (06/2006)
2. Kubota, Tetsuro: 1 article (06/2006)
3. Suto, Akihiko: 1 article (06/2006)
4. Fukushima, Masakazu: 1 article (06/2006)
5. Ikeda, Tadashi: 1 article (06/2006)
6. Takeshita, Toshio: 1 article (06/2006)
7. Kitajima, Masaki: 1 article (06/2006)
8. Takashima, Shigemitsu: 1 article (01/2004)
9. Sano, Muneaki: 1 article (01/2004)
10. Saek, Toshiaki: 1 article (01/2004)

Related Diseases

1. Neoplasms (Cancer)
2. Thiamine Deficiency
3. Hepatocellular Carcinoma (Hepatoma)
4. Breast Neoplasms (Breast Cancer)

Related Drugs and Biologics

1. Fluorouracil (Carac)
2. Oxonic Acid
3. Orotate Phosphoribosyltransferase
4. Tegafur
5. potassium oxonate
6. gimeracil
7. docetaxel (Taxotere)
8. fluorocitrate

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)