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Poloxamer (Poloxamer 407)

A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)
Also Known As:
Poloxamer 407; Poloxamers; Pluronic F-108; Pluronic F-127; Pluronic F-68; Pluronic F68; Pluronic L-101; Pluronic L-121; Pluronic L-81; Pluronics; Poloxalkol; Poloxamer 188; Poloxamer 213; Poloxamer 2930; Poloxamer 338; 188s, Poloxamer; 213s, Poloxamer; 2930s, Poloxamer; 338s, Poloxamer; 407s, Poloxamer; F68s, Pluronic; Pluronic F 108; Pluronic F 127; Pluronic F 68; Pluronic F108; Pluronic F127; Pluronic F68s; Pluronic L 101; Pluronic L 121; Pluronic L 81; Pluronic L101; Pluronic L121; Pluronic L81; Poloxalkols; Poloxamer 188s; Poloxamer 213s; Poloxamer 2930s; Poloxamer 338s; Poloxamer 407s; Pluronic; alpha-Hydro-omega-hydroxypoly(oxyethylene)a-poly(oxopropylene)b-poly(oxyethylene)a block copolymer
Networked: 1055 relevant articles (108 outcomes, 192 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Kabanov, Alexander V: 22 articles (04/2022 - 08/2002)
2. Tae, Giyoong: 15 articles (01/2022 - 05/2010)
3. Batrakova, Elena V: 14 articles (01/2020 - 08/2002)
4. Johnston, Thomas P: 14 articles (11/2017 - 06/2003)
5. Zhang, Wei: 12 articles (11/2021 - 08/2010)
6. Fang, Xiaoling: 12 articles (04/2016 - 06/2007)
7. Sha, Xianyi: 11 articles (09/2021 - 06/2007)
8. Alakhov, Valery Yu: 11 articles (05/2010 - 08/2002)
9. Kwon, Ick Chan: 10 articles (10/2018 - 05/2010)
10. Exner, Agata A: 9 articles (01/2019 - 08/2005)

Related Diseases

1. Neoplasms (Cancer)
2. Wounds and Injuries (Trauma)
3. Breast Neoplasms (Breast Cancer)
4. Myocardial Infarction
5. Hyperlipidemias (Hyperlipidemia)

Related Drugs and Biologics

1. Micelles
2. Hydrogels
3. Poloxamer (Poloxamer 407)
4. Surface-Active Agents (Surfactants)
5. Chitosan
6. Paclitaxel (Taxol)
7. UCON 50-HB-5100 (F127)
8. Curcumin
9. Acids
10. Doxorubicin (Adriamycin)

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Injections
4. Lasers (Laser)
5. Photochemotherapy (Photodynamic Therapy)