Pancreatic Extracts

Extracts prepared from pancreatic tissue that may contain the pancreatic enzymes or other specific uncharacterized factors or proteins with specific activities. PANCREATIN is a specific extract containing digestive enzymes and used to treat pancreatic insufficiency.

Also Known As:

Networked: 153 relevant articles (12 outcomes, 11 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Pezzilli, Raffaele: 4 articles (01/2020 - 04/2009)
2.	de Leiva-Hidalgo, Alberto: 3 articles (11/2023 - 12/2022)
3.	de Leiva-Pérez, Alejandra: 3 articles (11/2023 - 12/2022)
4.	Rostène, William: 2 articles (01/2022 - 01/2021)
5.	Park, Hae-Sim: 2 articles (01/2010 - 09/2002)
6.	Lubinsky, Mark: 1 article (01/2023)
7.	Wright, James R: 1 article (03/2022)
8.	Gerstein, Hertzel C: 1 article (12/2021)
9.	Rutty, Christopher J: 1 article (12/2021)
10.	De Meyts, Pierre: 1 article (01/2021)

Related Diseases

1.	Chronic Pancreatitis 06/15/1993 - "[Use of pancreatic extracts in chronic pancreatitis]." 07/01/1984 - "Chronic administration of pancreatic extract to patients with chronic pancreatitis decreased both basal and stimulated pancreatic exocrine secretion." 04/01/1995 - "Chronic supplementation with pancreatic extract is not beneficial in the management of recurrent pain in patients with chronic pancreatitis." 09/01/2020 - "Study of the gastrointestinal bioavailability of a pancreatic extract product (Zenpep) in chronic pancreatitis patients with exocrine pancreatic insufficiency." 08/01/1999 - "Statistical analysis demonstrated no benefit of the application of porcine pancreatic extracts to relieve pain in chronic pancreatitis. "
2.	Exocrine Pancreatic Insufficiency 09/01/2005 - "Canine exocrine pancreatic insufficiency treated with porcine pancreatic extract." 06/01/1996 - "Exocrine pancreatic insufficiency, which occurred at age 9, was treated with pancreatic extracts. " 01/01/1996 - "MCTs are absorbed better than LCTs in the presence of pancreatic insufficiency but require pancreatic extracts for optimal absorption. " 08/01/1993 - "Pancreatic extracts are necessary for the absorption of elemental and polymeric enteral diets in severe pancreatic insufficiency." 01/01/1993 - "In some patients, however, pancreatic insufficiency is severe enough to cause malabsorption, which can be effectively corrected by oral pancreatic extracts."
3.	Pain (Aches) 01/01/1992 - "We conclude that pancreatic extracts are not very efficient in lowering pain." 04/01/1995 - "Chronic supplementation with pancreatic extract is not beneficial in the management of recurrent pain in patients with chronic pancreatitis." 08/01/1999 - "Statistical analysis demonstrated no benefit of the application of porcine pancreatic extracts to relieve pain in chronic pancreatitis. " 01/01/1992 - "We conducted a prospective placebo-controlled double blind multicenter study to investigate the effect of porcine pancreatic extracts on pain in chronic pancreatitis. " 01/01/1992 - "Treatment of pain with pancreatic extracts in chronic pancreatitis: results of a prospective placebo-controlled multicenter trial."
4.	Cystic Fibrosis (Mucoviscidosis) 10/01/1997 - "Oral pancreatic extracts were not discontinued in the children with cystic fibrosis. " 06/01/1996 - "Pancreatic extracts are essential in the treatment of the majority of cystic fibrosis patients. " 06/01/1987 - "Comparison of four pancreatic extracts in cystic fibrosis." 01/01/1981 - "It is concluded that pancreatic extract supplementation alone is not sufficient to normalise the digestion in cystic fibrosis." 10/01/1977 - "The risk of pancreatic extract to those handling it, and possibly also to patients suffering from cystic fibrosis, is emphasized."
5.	Steatorrhea 12/01/2016 - "The mean units of the pancreatic extracts administered to the patients with steatorrhea were significantly increased before and after the meetings. " 01/01/1996 - "Steatorrhea was the same when MCTs and LCTs were consumed together with pancreatic extracts. " 01/01/1994 - "This pilot study demonstrates that the tested pancreatic extract very effectively corrects pancreatic steatorrhea in a simple low-dose regimen. " 01/01/1987 - "Inasmuch as the abnormal TBT results in patients with advanced alcohol-induced lesions did not correct with pancreatic extract, the test may not accurately differentiate pancreatic from nonpancreatic steatorrhea in some alcoholics." 04/14/2009 - "The relationships between pancreatic maldigestion, intestinal ecology and intestinal inflammation have not received particular attention, even if in clinical practice these mechanisms may be responsible for the low efficacy of pancreatic extracts in abolishing steatorrhea in some patients. "

Related Drugs and Biologics

1.	Acids
2.	Enzymes
3.	Vitamin B 12 (Cyanocobalamin)
4.	Proteins (Proteins, Gene)
5.	Hormones (Hormone)
6.	Hypoglycemic Agents (Hypoglycemics)
7.	Ceruletide
8.	Bile Acids and Salts (Bile Acids)
9.	Pancrex V
10.	Secretin

Related Therapies and Procedures

1.	Pancreatectomy
2.	Therapeutics
3.	Enzyme Replacement Therapy
4.	Ablation Techniques
5.	Fat-Restricted Diet (Diet, Fat Restricted)