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Lens Subluxation

Incomplete rupture of the zonule with the displaced lens remaining behind the pupil. In dislocation, or complete rupture, the lens is displaced forward into the anterior chamber or backward into the vitreous body. When congenital, this condition is known as ECTOPIA LENTIS.
Also Known As:
Lens Dislocation and Subluxation; Dislocation, Lens; Dislocations, Lens; Lens Dislocations; Lens Subluxations; Subluxation, Lens; Subluxations, Lens; Lens Dislocation
Networked: 118 relevant articles (3 outcomes, 2 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Cataract (Cataracts)
2. Marfan Syndrome (Marfan's Syndrome)
3. Wounds and Injuries (Trauma)
4. Rupture
5. Glaucoma

Experts

1. Duma, Stefan M: 4 articles (04/2012 - 10/2005)
2. Khan, Arif O: 2 articles (03/2015 - 04/2014)
3. Mashkova, N A: 2 articles (07/2014 - 11/2012)
4. Voronin, G V: 2 articles (07/2014 - 11/2012)
5. Tsou, Mei-Yung: 2 articles (11/2012 - 09/2002)
6. Liu, Yizhi: 2 articles (04/2012 - 05/2002)
7. Bisplinghoff, Jill A: 2 articles (04/2012 - 01/2009)
8. Tsuji, Takashi: 2 articles (01/2012 - 11/2011)
9. Saito, Masahiro: 2 articles (01/2012 - 11/2011)
10. Endriss, Daniela: 2 articles (03/2010 - 03/2010)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Lens Subluxation:
1. PhysostigmineIBA
2. Retinaldehyde (Retinal)IBA
3. fibrillinIBA
4. NeodymiumIBA
5. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/01/2014 - "After treatment, IVIs of VEGF were given and vitreous tap was performed three times, followed by clinical observation of lens subluxation and scanning electronic microscope evaluation of the zonular fibers. "
01/01/2012 - "The mean vitreous level of VEGF was 15.14 ± 5.22 pg/ml in eyes with grade B PVR, 99.15 ± 38.58 pg/ml in eyes with grade C PVR, 4,534.01 ± 1,193.28 pg/ml in eyes with vitreous hemorrhage secondary to PDR, 5,157.29 ± 969.44 pg/ml in eyes with vitreous hemorrhage and tractional retinal detachment secondary to PDR, and 16.19 ± 5.76 pg/ml in eyes of the control group with traumatic lens dislocation. "
01/01/2014 - "After IVIs of plasmin and SF6, and VEGF and vitreous tap had been performed one to three times, lens subluxation was noted in 0%, 43%, 71%, 71%, and 86% of the eyes in group 1. After IVIs of plasmin, VEGF, and vitreous tap had been performed one to three times, lens subluxation was noted in 11%, 22%, 44%, 44%, and 67% of the eyes in group 2. The eyes in group 3 and 4 did not show signs of lens subluxation after VEGF IVIs and vitreous tap. "
01/01/2014 - "The incidence of lens subluxation increased following plasmin injections in the eyes, and this was aggravated by the subsequent high VEGF level in the eyes and vitreous tapping. "
01/01/2014 - "To investigate the rate of lens subluxation following plasmin and/or SF6 injections in eyes, and whether a subsequent elevated level of vascular endothelial growth factor (VEGF) and vitreous tap would aggravate subluxation. "
6. SiliconesIBA
7. Pyridoxine (Pyridoxin)FDA LinkGeneric
8. Polypropylenes (Polypropylene)IBA
9. Methionine (L-Methionine)FDA Link
10. Sulfite oxidase deficiencyIBA

Therapies and Procedures

1. Intraocular Lenses (Intraocular Lens)
2. Vitrectomy
3. Phacoemulsification
4. Lenses
5. Cataract Extraction