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Absorbable Gelatin Sponge

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Sterile, gelatin-base surgical sponge applied topically as an adjunct to hemostasis when the control of bleeding by conventional procedures is ineffective to reduce capillary ooze or is impractical. (From AMA Drug Evaluations Annual, 1994, p797)

Also Known As:

Gelatin Sponge, Absorbable; Gelaspon; Gelfoam; Absorbable Gelatin Sponges; Gelatin Sponges, Absorbable; Sponge, Absorbable Gelatin; Sponges, Absorbable Gelatin

Networked: 509 relevant articles (20 outcomes, 38 trials/studies) for this Therapy, Comments

Relationship Network

Therapy Context: Research Results

Equipment and Supplies
- Surgical Equipment: 27
  - Surgical Sponges: 66
    - Absorbable Gelatin Sponge: 509

Experts

1.	Weaver, Fred A: 3 articles (12/2008 - 05/2002)
2.	Park, Haekyun: 2 articles (11/2008 - 10/2008)
3.	Jang, Chul Ho: 2 articles (11/2008 - 10/2008)
4.	Cho, Yong Bum: 2 articles (11/2008 - 10/2008)
5.	Shan, Hong: 2 articles (04/2008 - 03/2004)
6.	Baker, Cheryl H: 2 articles (08/2005 - 07/2002)
7.	Reszka, R: 2 articles (03/2001 - 08/2000)
8.	Pohlen, U: 2 articles (03/2001 - 08/2000)
9.	Buhr, H J: 2 articles (03/2001 - 08/2000)
10.	Binnenhei, M: 2 articles (03/2001 - 08/2000)

Related Diseases

1.	Hemorrhage 07/01/2007 - "Analysis of the results demonstrated that the haemostatic agents are effective in controlling hemorrhage; they stimulate osteogenesis, featuring a pattern of osseous tissue formation similar to the control pattern, although the amount of osseous trabeculae was superior, especially in the Gelfoam group in the periods of 7 and 14 days; 30 days after surgery, the delay in tissue healing in the control group in relation to the experimental groups started to decrease, and the control and experimental groups exhibited similar tissue repair after 45 days, when all the groups exhibited secondary osseous tissue." 12/01/1981 - "In 16 patients, gelfoam embolization of the bronchial artery was effective in causing immediate cessation of the hemorrhage. " 08/01/2006 - "The insertion of an absorbable gelatin sponge into the extraction socket was found to be a very useful method to prevent postoperative bleeding problems." 08/01/2007 - "Blinded study drug was applied topically to bleeding sites with an absorbable gelatin sponge. " 05/01/1987 - "Following a pilot study a controlled trial was carried out to assess the effect of absorbable gelatin sponge on reducing the bleeding from microvascular anastomoses of the femoral arteries and veins of rats. " Order ALL the reference details at left...
2.	Neoplasms (Cancer) 07/01/2006 - "Cytokine-containing gelfoam implants at a postsurgical tumor excision site to stimulate local immune reactivity." 03/15/2004 - "There were no significant differences in survival rate in the Gelfoam group with regard to the number of tumor and Child class (P>0.05). " 03/01/2003 - "R3230Ac tumor fragments or cells in Gelfoam were aseptically implanted into the nipple sinus. " 05/01/2000 - "The postoperative pathological findings showed that the entity of the tumor was congested with gelfoam. " 05/01/2000 - "METHOD: Under digital subtraction angiographic control, superselectively catheterizing the external carotid artery, thus occluding the terminal branches of the feeding arteries of the tumor with particles of liquidized gelfoam. " Order ALL the reference details at left...
3.	Fibrosis (Cirrhosis) 04/01/2009 - "The Gelfoam group was associated with the best outcome with regard to the number of engrafted donor cells (p = 0.03 versus myoblasts) and the reduction of fibrosis (p = 0.02 and p = 0.04 versus the control and myoblast groups, respectively). " 04/01/1997 - "Although the sponge is generally well tolerated, fibrosis occasionally forms in the mesotympanum; some studies indicated that the absorbable gelatin sponge may be responsible. " 06/01/1990 - "Gelfoam did not inhibit but actually appeared to increase fibrosis formation. " 01/01/1980 - "Gelfoam failed to prevent fibrosis. " 05/01/1975 - "With Gelfoam, although the embolic material was also pushed peripherally into the branches of the splenic artery in several of the dogs, the depression of hematologic function was prolonged, and moderate splenic parenchymal fibrosis was seen. " Order ALL the reference details at left...
4.	Dry Socket (Alveolar Osteitis) 01/01/1990 - " Absorbable gelatin sponge alone is not effective in reducing the incidence of alveolar osteitis. " 01/01/1992 - "This double blind clinical study was undertaken to evaluate the effectiveness of locally applied clindamycin in Gelfoam in reducing the incidence of dry socket formation after third molar surgery. " 08/01/1988 - "This clinical study was undertaken to evaluate the effectiveness of locally applied 9-aminoacridine in Gelfoam in reducing the incidence of dry socket formation after third molar extractions. " 08/01/1988 - "An evaluation of 9-aminoacridine/Gelfoam to reduce dry socket formation." 05/01/1982 - "Prevention of dry socket with local application of Terra-Cortril in gelfoam." Order ALL the reference details at left...
5.	Hepatocellular Carcinoma (Hepatoma) 05/01/1987 - "Gelfoam seemed to be more effective in the treatment of hepatoma, but the damage to normal tissue was more severe with this embolic material." 08/01/1984 - "A histopathologic study was done on livers from 14 patients who underwent surgery for hepatocellular carcinoma and who had been pretreated by a combination of intra-arterial embolization of Gelfoam (Upjohn) plus intra-arterial chemotherapy. " 09/01/2003 - "From February 1994 to April 2000, 29 emergency gelfoam embolizations for spontaneous ruptured hepatocellular carcinoma (HCC) performed in 28 patients were retrospectively reviewed. " 06/01/2000 - "A randomized clinical trial comparing autologous blood clot and gelfoam in transarterial chemoembolization for inoperable hepatocellular carcinoma." 07/01/1990 - "Six patients with resectable hepatocellular carcinoma received this treatment, which in 3 of them was followed by embolization with Gelfoam of the segmental artery. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Gelatin
2.	Fibrin Tissue Adhesive (Fibrin Sealant)
3.	gelatin film
4.	Thrombin
5.	Iodized Oil (Lipiodol)
6.	Polyvinyl Alcohol
7.	Carboplatin (JM8)
8.	Collagen
9.	Mitomycin (Mitomycin-C)
10.	Polytetrafluoroethylene (Teflon)

Related Therapies and Procedures

1.	Transplants (Transplant)
2.	Balloon Occlusion
3.	Angioplasty (Angioplasties)
4.	Carotid Endarterectomy
5.	Sutures (Suture)

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