Antiglaucoma Agents

Agents used to preserve visual function by decreasing INTRAOCULAR PRESSURE (IOP) by targeting the AQUEOUS HUMOR.

Also Known As:

Anti Glaucoma Medications; Drug, Anti-Glaucoma; Drugs, Anti-Glaucoma; Medications, Anti-Glaucoma; Medications, Antiglaucoma; Anti-Glaucoma Agent; Anti-Glaucoma Agents; Anti-Glaucoma Drug; Anti-Glaucoma Drugs; Anti-Glaucoma Medications; Antiglaucoma Drugs; Antiglaucoma Medications

Networked: 491 relevant articles (39 outcomes, 45 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Chemical Actions and Uses
- Pharmacologic Actions: 160
  - Therapeutic Uses: 47080
    - Antiglaucoma Agents: 491

Experts

1.	Tanito, Masaki: 8 articles (06/2022 - 02/2002)
2.	Supuran, Claudiu T: 7 articles (07/2012 - 08/2006)
3.	Almobarak, Faisal A: 6 articles (08/2022 - 05/2017)
4.	Al-Obeidan, Saleh A: 6 articles (01/2020 - 01/2013)
5.	Baudouin, Christophe: 6 articles (03/2014 - 10/2003)
6.	Senthil, Sirisha: 5 articles (02/2021 - 12/2013)
7.	Kondkar, Altaf A: 5 articles (01/2020 - 09/2016)
8.	Sultan, Tahira: 5 articles (01/2020 - 09/2016)
9.	Abu-Amero, Khaled K: 5 articles (10/2018 - 01/2013)
10.	Azad, Taif A: 4 articles (01/2020 - 09/2016)

Related Diseases

1.	Glaucoma 10/05/2016 - "Recently, introduction of preservative-free anti-glaucoma agents has become an important step towards improved glaucoma care by eliminating the negative effects of preservatives on the eye surface. " 04/01/2022 - "After 2 years, all performed glaucoma surgeries achieved a significant reduction in IOP and the number of antiglaucoma medications. " 01/01/2021 - "Ahmed glaucoma valve (AGV) implantation led to a significant reduction in intraocular pressure (IOP) and in antiglaucoma medications in vitrectomized eyes in previously nonglaucomatous eyes. " 04/01/2016 - "Glaucoma and the number of antiglaucoma drugs are associated with a significant reduction in tear secretion. " 09/26/2021 - "However, at the end of the follow-up, more patients achieved an IOP < 18 mmHg in Group 1 than in Group 2. Despite the need for more anti-glaucoma medications, repeat XEN Gel implantation appears to show promising results in patients with previously failed anti-glaucoma procedures, owing to its minimal invasiveness."
2.	Cataract (Cataracts) 09/01/2013 - "Both the treatment group and the control group had lowered intraocular pressure, reduced the use of antiglaucoma medications, and improved vision in patients with PACG and cataract. " 05/01/2017 - "However, more antiglaucoma medications were needed to control the IOP after cataract surgery at the last follow-up [1.59 medications (±1.4) in the study group and 0.50 medications (±0.7) in the control group; P=0.009]. " 11/16/2023 - "For overall success, other risk factors for failure were lower preoperative IOP (for 1-mmHg increase, HR: 0.934, p=0.005), higher number of preoperative antiglaucoma agents (HR: 1.626, p<0.001), and Microshunt combined with cataract surgery (HR: 1.526, p=0.033). " 04/01/2022 - "One-tenth of phakic eyes received cataract surgery while 2% had a pressure response requiring anti-glaucoma medications. " 01/01/2022 - "Patients consisted of adults with OAG on antiglaucoma medications who had cataract surgery combined with one iStent implantation. "
3.	Open-Angle Glaucoma (Glaucoma, Open Angle) 10/01/2021 - "ABIC achieved a statistically significant reduction in IOP and anti-glaucoma medications through 12 months, while maintaining a favourable safety profile in mild-to-severe open-angle glaucoma." 11/01/2020 - "We aimed to compare the efficacy of ab externo and ab interno 360-degree ST in reducing IOP, decreasing the number of antiglaucoma medications required, and decreasing the rates of intraoperative/postoperative complications in adults with open-angle glaucoma (OAG). " 02/01/2014 - "The purpose of the present study was to elucidate the effects of several anti-glaucoma medications on the circadian intraocular pressure (IOP) fluctuations in patients with primary open-angle glaucoma (POAG). " 03/01/2013 - "To study drug use pattern in patients of primary open angle glaucoma (POAG) and to analyze the cost of different anti-glaucoma medications. " 02/01/2014 - "Effects of several anti-glaucoma medications on the circadian intraocular pressure fluctuations in patients with primary open-angle glaucoma."
4.	Ocular Hypertension (Glaucoma, Suspect) 07/01/2014 - "In the absence of head-to-head comparisons with other anti-glaucoma drugs, an adjusted, indirect comparison meta-analysis was performed using data from 21 randomized clinical trials in patients with POAG/ocular hypertension. " 06/01/2023 - "Multiple linear regression revealed that, among all the clinical factors, axial length (AL) and ocular hypertension (intraocular pressure (IOP) > 21 mmHg or the use of antiglaucoma medications) before SO removal were positively and significantly associated with the SOI (all P < 0.05). " 01/01/2021 - "Patients with intraocular pressure (IOP) > 21 mmHg or the use of antiglaucoma medications at the time of SO removal had a higher total SO emulsification grade, were younger, and were more frequently male (all P < 0.05) than patients without ocular hypertension. " 01/01/2021 - "Secondary ocular hypertension developed in one-third of patients receiving injection which was transient and successfully managed with topical anti-glaucoma medications only. " 03/01/2016 - "Fewer preoperative antiglaucoma agents, older age, and more time from PSTA to ocular hypertension were correlated with more rapid IOP normalization after subtenon TA removal."
5.	Angle-Closure Glaucoma (Glaucoma, Angle Closure) 01/01/2023 - "Ultrasound cyclo plasty (UCP) can be useful in decreasing the intraocular pressure (IOP) and burden of antiglaucoma medications in eyes with primary angle closure glaucoma (PACG). " 09/01/2014 - "A 35-year-old male patient, diagnosed with acute angle-closure glaucoma, did not improve despite intensive treatment with antiglaucoma medications. " 11/09/2010 - "Both phacotrabeculectomy and short-term anti-glaucoma medications can decrease the MUC5AC in the tear fluid of primary angle-closure glaucoma patients. " 04/01/2001 - "To study the efficacy and safety of diode laser peripheral iridoplasty as a first-line treatment of acute primary angle-closure glaucoma (PACG) without the use of systemic anti-glaucoma medications. " 12/01/2022 - "Such was our case an elderly primigravida 10 weeks of gestation who had an acute episode of angle closure glaucoma with diminishing vision, who was managed both medically (anti-glaucoma drugs) and surgically (trabeculectomy). "

Related Drugs and Biologics

1.	Timolol (Blocadren)
2.	Brimonidine Tartrate (Alphagan)
3.	dorzolamide (Trusopt)
4.	Latanoprost (Xalatan)
5.	Benzalkonium Compounds (Benzalkonium Chloride)
6.	Fluorouracil (Carac)
7.	Adrenal Cortex Hormones (Corticosteroids)
8.	K-115
9.	rho-Associated Kinases
10.	Dendrimers (Dendrons)

Related Therapies and Procedures

1.	Phacoemulsification
2.	Trabeculectomy (Trabeculoplasty)
3.	Therapeutics
4.	Semiconductor Lasers
5.	Cataract Extraction