Ex utero Intrapartum Treatment Procedures

Prenatal interventions to manage fetal anomalies or FETAL DISEASES ex utero while maintaining the uteroplacental circulation during obstetric delivery. EXIT procedures are divided into EXIT-to-airway; EXIT-to-ECMO; and EXIT-to-resection.

Also Known As:

EXIT Procedure; EXIT to Airway; EXIT to Airway Procedure; EXIT to ECMO Procedure; EXIT to Extra Corporeal Membrane Oxygenation; EXIT to Extra Corporeal Membrane Oxygenation Procedure; EXIT to Resection; EXIT to Resection Procedure; EXIT-to-Airway Procedures; EXIT-to-Airways; EXIT-to-ECMO Procedures; EXIT-to-Extra-Corporeal Membrane Oxygenations; EXIT-to-Resection Procedures; EXIT-to-Resections; Procedure, EXIT-to-Airway; Procedure, EXIT-to-Resection; EXIT Procedures; EXIT-to-Airway; EXIT-to-Airway Procedure; EXIT-to-ECMO Procedure; EXIT-to-Extra-Corporeal Membrane Oxygenation; EXIT-to-Extra-Corporeal Membrane Oxygenation Procedure; EXIT-to-Resection; EXIT-to-Resection Procedure; Ex utero Intrapartum Technique Procedures; Ex-utero Intrapartum Technique Procedures; Ex-utero Intrapartum Treatment Procedures

Networked: 131 relevant articles (6 outcomes, 5 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Adzick, N Scott: 6 articles (10/2021 - 03/2002)
2.	Howell, Lori J: 6 articles (10/2021 - 03/2002)
3.	Flake, Alan W: 6 articles (10/2013 - 03/2002)
4.	Hedrick, Holly L: 5 articles (10/2021 - 06/2005)
5.	Crombleholme, Timothy M: 5 articles (01/2009 - 03/2002)
6.	Johnson, Mark P: 4 articles (10/2013 - 03/2002)
7.	Lee, Timothy C: 3 articles (01/2022 - 01/2013)
8.	Lim, Foong-Yen: 3 articles (03/2015 - 01/2009)
9.	Myers, Laura B: 3 articles (02/2007 - 03/2002)
10.	Hirose, Shinjiro: 3 articles (03/2004 - 03/2003)

Related Diseases

1.	Airway Obstruction (Choking) 05/01/2006 - "The lessons learned in the development of the principles that underlie the EXIT procedure have improved outcomes when applied in other conditions, most notably in cases of airway obstruction. " 02/01/2015 - "We report the case of an infant with severe lymphatic malformation necessitating ex-utero intrapartum treatment (EXIT) procedure and examine recent advances in high resolution ultrasonography and magnetic resonance imaging, which allow for improved prenatal diagnosis of lesions that cause critical airway obstruction in the neonate. " 08/04/2023 - "The aim of this study was to report outcomes of the first cohort of fetuses with neck masses and suspected airway obstruction managed with fetal laryngoscopy (FL) and fetal endoscopic tracheal intubation (FETI) to secure fetal airways and avoid ex-utero intrapartum treatment (EXIT) procedure. " 06/01/2003 - "While the technique of tracheal occlusion remains under study in clinical trials, EXIT procedures have been shown to be useful for management of other causes of foetal airway obstruction." 08/04/2023 - "In fetuses with neck masses and suspected airway obstruction FL and FETI are feasible and could replace EXIT procedures with good maternal and perinatal outcomes."
2.	Neoplasms (Cancer) 04/01/2014 - "To the best of our knowledge, this is a unique case of congenital peribronchial myofibroblastic tumor that underwent comprehensive prenatal evaluation and EXIT procedure with good outcome." 04/23/2021 - "Prenatal diagnosis, therapeutic options and ex utero intrapartum treatment (EXIT) procedures are discussed for the diagnosis and management of this very rare tumor." 01/01/2020 - "Twin A was delivered via EXIT to airway while Twin B had debulking of the tumor on placental support, with subsequent airway securement through a tracheostomy. " 06/01/2017 - "An EXIT procedure should be considered when airway compromise by tumor compression is suspected. " 02/01/2017 - "EXIT procedure and surgical removal of the tumor was associated with good prognosis."
3.	Teratoma (Teratoid Tumor) 05/01/2011 - "The number of cases in which neonates have survived epignathus teratomas has increased in the past decade due to improved prenatal imaging and the development of the EXIT procedure. " 06/01/2012 - "The purpose of this study is to present the outcome and technical details of the Ex Utero Intrapartum Treatment (EXIT) procedure performed in the management of the fetus with a giant cervical teratoma. " 07/01/2023 - "Many teratomas are diagnosed prenatally and can be quite large, often requiring Ex Utero Intrapartum Treatment (EXIT) procedure at birth to establish a safe airway. " 01/01/2023 - "Case report: EXIT procedure in cervical teratoma during pregnancy." 04/01/2018 - "Massive fetal cervical teratoma managed with the ex utero intrapartum treatment (EXIT) procedure."
4.	Pathologic Constriction (Stenosis) 02/01/2018 - "Due to airway stenosis, the patient was delivered by the ex utero intrapartum treatment (EXIT) procedure at 36 weeks of pregnancy. " 02/01/2018 - "The EXIT procedure could be effective for infants with upper respiratory stenosis by head and neck tumor diagnosed prenatally. " 01/01/2022 - "Specifically, we discuss some of the exciting trends in surgical management of vocal fold paralysis, laryngeal clefts, subglottic stenosis, tracheobronchomalacia as well as the role of ex utero intrapartum therapy (EXIT procedures). " 05/01/2011 - "Indications for EXIT procedures were: 11 cervical teratomas, 9 diaphragmatic hernias, 4 pulmonary airway malformations, 4 micrognathias, 3 vascular malformations, 3 CHAOS, and 2 aortic stenoses. "
5.	Asphyxia (Suffocation) 10/01/2006 - "A well-planned ex utero intrapartum treatment (EXIT) procedure for aspiration and decompression of the cystic lesion is simple, efficacious and effective in securing a patent airway before the fetus is completely delivered, and may prevent lifelong neurodevelopmental complications associated with perinatal asphyxia in such cases. "

Related Drugs and Biologics

1.	Anesthetics (Anesthetic Agents)
2.	Oxygen (Dioxygen)
3.	Isoflurane

Related Therapies and Procedures

1.	Decompression
2.	Tracheotomy
3.	Anesthesia
4.	Airway Management
5.	Tracheostomy