KRIT1 Protein
A microtubule-associated protein consisting of four ANKYRIN REPEATS and a C-terminal FERM DOMAIN. It links the CYTOSKELETON to CELL JUNCTIONS via integrin cytoplasmic domain-associated protein-1 and plays an important role in regulating cell proliferation and integrity of endothelial cell junctions. It is also involved in REACTIVE OXYGEN SPECIES metabolism. Mutations in the KRIT1 gene are associated with type I CEREBRAL CAVERNOUS MALFORMATIONS.
Also Known As:
Cerebral Cavernous Malformations 1 Protein; Krev Interaction Trapped Protein 1
Networked: 5
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Abdelilah-Seyfried, Salim:
1 article
(10/2019)
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2. | Donat, Stefan:
1 article
(10/2019)
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3. | Fischer, Dorothea:
1 article
(10/2019)
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4. | Freund, Christian:
1 article
(10/2019)
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5. | Kuropka, Benno:
1 article
(10/2019)
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6. | Lourenço, Marta:
1 article
(10/2019)
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7. | Otten, Cécile:
1 article
(10/2019)
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8. | Paolini, Alessio:
1 article
(10/2019)
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9. | Rödel, Claudia Jasmin:
1 article
(10/2019)
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10. | Aquila, Giorgio:
1 article
(10/2019)
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