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2- (3,4- dimethoxy- phenyl)- 4,5- dihydro- 1H- imidazole

structure in first source

Also Known As:

2-DMPI

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Bonacorso, Helio Gauze: 1 article (07/2013)
2.	Fachinetto, Roselei: 1 article (07/2013)
3.	Ferreira, Juliano: 1 article (07/2013)
4.	Machado, Pablo: 1 article (07/2013)
5.	Martins, Marcos Antônio Pinto: 1 article (07/2013)
6.	Oliveira, Sara Marchesan: 1 article (07/2013)
7.	Pinheiro, Francielle de Vargas: 1 article (07/2013)
8.	Pinheiro, Kelly de Vargas: 1 article (07/2013)
9.	Villarinho, Jardel Gomes: 1 article (07/2013)
10.	Zanatta, Nilo: 1 article (07/2013)

Related Diseases

1.	Neuralgia (Stump Neuralgia) 07/01/2013 - "Because the analgesic potential of monoamine oxidase-A (MAO-A) inhibitors is understudied, we evaluated the potential antinociceptive effect of the reversible MAO-A inhibitors moclobemide and 2-(3,4-dimethoxy-phenyl)-4,5-dihydro-1H-imidazole (2-DMPI) in a mouse neuropathic pain model induced by chronic constriction injury (CCI) of the sciatic nerve. "
2.	Hyperalgesia 07/01/2013 - "Moclobemide (100-300 μmol/kg, s.c.) and 2-DMPI (30-300 μmol/kg, s.c.) treatments were able to reverse the CCI-induced hyperalgesia, with 50% inhibitory dose (ID50) values of 39 (18-84) and 11 (4-33) μmol/kg, and maximum inhibition (Imax) values of 88±14 and 98±15%, respectively, at the 300 μmol/kg dose. "

Related Drugs and Biologics

1.	Moclobemide (Arima)
2.	Monoamine Oxidase (MAO)
3.	Analgesics (Analgesic Drugs)