medioresinol

has both leishmanicidal and antifungal activities; isolated from Sambucus williamsii; structure in first source

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

1.	Neoplasms (Cancer) 09/05/2022 - "The evidence from clinical and observational studies suggests that human microbiota metabolites (enterolactone, enterodiol) of dietary lignans (secoisolariciresinol, pinoresinol, lariciresinol, matairesinol, syringaresinol, medioresinol, and sesamin) are associated with a reduced risk of some hormone-dependent cancers. "
2.	Mitochondrial Diseases (Mitochondrial Disease) 08/01/2012 - "These apoptotic phenomena represent that oxidative stress and mitochondria dysfunctions by inducing the phytochemical (+)-Medioresinol must be an important factors of the apoptotic process in C. albicans. "
3.	Cardiovascular Diseases (Cardiovascular Disease) 08/01/2012 - "(+)-Medioresinol is known to possess a lesishmanicidal activity and cardiovascular disease risk reduction but its antifungal effects have not yet been identified. "
4.	Brain Injuries (Brain Injury) 01/01/2021 - "However, it is not known whether BMVECs undergo pyroptosis after ischemic stroke and whether PGC-1α activator Medioresinol (MDN) we discovered may be useful against pyroptosis of endothelial cells and ischemic brain injury. "
5.	Bacterial Infections (Bacterial Infection) 08/01/2013 - "It concludes that (+)-Medioresinol has potential as a therapeutic agent and adjuvant for treatment of bacterial infection."

1.	Lignans
2.	Hormones (Hormone)
3.	pinoresinol
4.	matairesinol
5.	secoisolariciresinol
6.	lariciresinol
7.	sesamin
8.	syringaresinol
9.	2,3-bis(3'-hydroxybenzyl)butane-1,4-diol (enterodiol)
10.	2,3-bis(3'-hydroxybenzyl)butyrolactone (enterolactone)