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FPP(RGD)2

a PET imaging agent for alphavbeta3 integrin; structure in first source

Also Known As:

(18F)FPP(RGD)2; 18F-FPPRGD2; 2-fluoropropionyl-PEG3-E(c(RGDyk))2

Networked: 4 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - FPP(RGD)2: 4
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - FPP(RGD)2: 4

Experts

1.	Chen, Xiaoyuan: 2 articles (01/2016 - 01/2011)
2.	Shen, Baozhong: 2 articles (01/2016 - 01/2011)
3.	Sun, Xilin: 2 articles (01/2016 - 01/2011)
4.	Baratto, Lucia: 1 article (07/2019)
5.	Duan, Heying: 1 article (07/2019)
6.	Fan, Alice C: 1 article (07/2019)
7.	Hatami, Negin: 1 article (07/2019)
8.	Iagaru, Andrei: 1 article (07/2019)
9.	Park, Sonya: 1 article (07/2019)
10.	Thompson, Holly M: 1 article (07/2019)

Related Diseases

1.	Neoplasms (Cancer) 04/01/2011 - "[(18)F]FPP(RGD)(2) small animal PET mouse tumor xenograft studies are reproducible with relatively low variability." 04/01/2011 - "Reproducibility study of [(18)F]FPP(RGD)2 uptake in murine models of human tumor xenografts." 01/01/2011 - "The tumor uptake of 18F-FPPRGD2 in the Abraxane-treated group was significantly lower on days 3 and 7 than at baseline but returned to the baseline level at days 14 and 21, indicative of relapse of the tumors after the treatment was halted. " 01/01/2016 - "Our previous studies revealed molecular alterations of tumor vessels, varying from immature to mature alterations, resulting from Abraxane, and demonstrated that the integrin-specific PET tracer 18F-FPPRGD2 can be used to noninvasively monitor such changes. " 04/01/2011 - "An (18)F-labeled PEGylated arginine-glycine-aspartic acid (RGD) dimer {[(18)F]FPP(RGD)(2)} has been used to image tumor α(v)β(3) integrin levels in preclinical and clinical studies. "
2.	Renal Cell Carcinoma (Grawitz Tumor) 07/01/2019 - "18F-FPPRGD2 PET/CT in patients with metastatic renal cell cancer."

Related Drugs and Biologics

1.	Integrins
2.	Albumin-Bound Paclitaxel
3.	Investigational Drugs
4.	aspartic acid glycine arginine

Related Therapies and Procedures

1.	Therapeutics