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vallesiachotamine

antiproliferative, from the leaves of Palicourea rigida (Rubiaceae) collected in the Brazilian Cerrado; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Indole Alkaloids: 200
    - vallesiachotamine: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - Indole Alkaloids: 200
        vallesiachotamine: 1
    - Indolizines: 3
      - Indolizidines: 2
        Indole Alkaloids: 200
        vallesiachotamine: 1

Experts

1.	Guillo, Lídia Andreu: 1 article (03/2012)
2.	Kato, Lucilia: 1 article (03/2012)
3.	Soares, Paula R O: 1 article (03/2012)
4.	de Oliveira, Cecília M A: 1 article (03/2012)
5.	de Oliveira, Pollyana Laurindo: 1 article (03/2012)

Related Diseases

1.	Necrosis 03/01/2012 - "Treatment of cells with 50 μM vallesiachotamine for 24 h caused extensive cytotoxicity and necrosis. " 03/01/2012 - "Our results demonstrated that the indole alkaloid vallesiachotamine exhibited important cytotoxicity toward human melanoma cells and that apoptosis and necrosis might be responsible for the observed events."
2.	Melanoma (Melanoma, Malignant) 03/01/2012 - "In vitro antiproliferative effects of the indole alkaloid vallesiachotamine on human melanoma cells." 03/01/2012 - "Our results demonstrated that the indole alkaloid vallesiachotamine exhibited important cytotoxicity toward human melanoma cells and that apoptosis and necrosis might be responsible for the observed events."

Related Drugs and Biologics

1.	Indole Alkaloids