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64Cu-CB-TE2A-sst2-ANT

a somatostatin receptor subtype 2 agonist; structure in first source

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - 64Cu-CB-TE2A-sst2-ANT: 1
Inorganic Chemicals: 9
- Coordination Complexes: 576
  - 64Cu-CB-TE2A-sst2-ANT: 1
Organic Chemicals: 133
- Coordination Complexes: 576
  - 64Cu-CB-TE2A-sst2-ANT: 1

Experts

1.	Achilefu, Samuel: 1 article (11/2008)
2.	Anderson, Carolyn J: 1 article (11/2008)
3.	Eiblmaier, Martin: 1 article (11/2008)
4.	Ferdani, Riccardo: 1 article (11/2008)
5.	Liang, Kexian: 1 article (11/2008)
6.	Sherman, Christopher D: 1 article (11/2008)
7.	Wadas, Thaddeus J: 1 article (11/2008)
8.	Zheleznyak, Alexander: 1 article (11/2008)

Related Diseases

1.

Neoplasms (Cancer)

11/01/2008 - "Small-animal imaging using 64Cu-CB-TE2A-sst2-ANT revealed excellent tumor-to-background contrast at 4 h after injection, and standardized uptake values remained high even after 24 h. "
11/01/2008 - "Both radiopharmaceuticals were also compared in vivo through biodistribution studies using healthy rats bearing AR42J tumors, and small-animal PET/CT of 64Cu-CB-TE2A-sst2-ANT was performed. "
11/01/2008 - "Receptor-binding studies were performed to determine the dissociation constant of the radiopharmaceutical 64Cu-CB-TE2A-sst2-ANT using AR42J rat pancreatic tumor cell membranes. "
11/01/2008 - "Tumor-to-blood and tumor-to-muscle ratios were determined to be better for 64Cu-CB-TE2A-sst2-ANT than those for 64Cu-CB-TE2A-Y3-TATE at the later time points, although liver and kidney uptake was significantly higher. "
11/01/2008 - "The PET radiopharmaceutical 64Cu-CB-TE2A-sst2-ANT is an attractive agent, worthy of future study as a PET radiopharmaceutical for the imaging of somatostatin receptor-positive tumors."

Related Drugs and Biologics

1.	Radiopharmaceuticals
2.	Somatostatin Receptors (Somatostatin Receptor)
3.	Somatostatin (Somatotropin Release-Inhibiting Factor)
4.	64Cu-CB-TE2A-Y3-TATE