HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Somatostatin (Somatotropin Release-Inhibiting Factor)

A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal.
Also Known As:
Somatotropin Release-Inhibiting Factor; Somatotropin Release Inhibiting Hormone; SRIH-14; Somatofalk; Somatostatin, Cyclic; Stilamin; Somatostatin 14; Somatotropin Release Inhibiting Factor; Cyclic Somatostatin; Somatostatin-14; Somatotropin Release-Inhibiting Hormone
Networked: 8960 relevant articles (743 outcomes, 1151 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Colao, Annamaria: 57 articles (01/2020 - 02/2003)
2. de Herder, Wouter W: 37 articles (05/2021 - 01/2002)
3. Hofland, Leo J: 36 articles (05/2022 - 12/2002)
4. Krenning, Eric P: 35 articles (05/2016 - 04/2002)
5. Schally, Andrew V: 34 articles (12/2020 - 02/2002)
6. Pivonello, Rosario: 33 articles (01/2021 - 02/2003)
7. Castaño, Justo P: 32 articles (01/2022 - 07/2009)
8. de Jong, Marion: 32 articles (09/2021 - 04/2003)
9. Culler, Michael D: 32 articles (06/2021 - 06/2003)
10. Schulz, Stefan: 31 articles (07/2022 - 11/2003)

Related Diseases

1. Neoplasms (Cancer)
2. Acromegaly
3. Hemorrhage
4. Carcinoid Tumor (Carcinoid)
5. Neuroendocrine Tumors (Neuroendocrine Tumor)

Related Drugs and Biologics

1. Octreotide (Sandostatin)
2. lanreotide (Somatuline)
3. Somatostatin Receptors (Somatostatin Receptor)
4. Hormones (Hormone)
5. Dopamine Agonists (Dopamine Agonist)
6. Growth Hormone (Somatotropin)
7. pasireotide
8. pegvisomant
9. Insulin (Novolin)
10. Insulin-Like Growth Factor I (IGF-1)

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Sclerotherapy
4. Radiotherapy
5. Aftercare (After-Treatment)