Trichilemmal Cyst 1

A hereditary, autosomal dominant type of epidermal cyst that occurs primarily on the scalp. These cysts are easily enucleated, and are characterized by a well-keratinized epidermal wall surrounding semisolid hair keratin. They appear during adolescence as firm, smooth, white-walled cysts without a puncta. This phenotype has been mapped to chromosome 3p24-p21.2. OMIM: 609649

Also Known As:

TRICY1; Tricholemmal Cyst

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Neoplasms: 1324753
- Cysts: 25757
  - Epidermal Cyst: 532
    - Trichilemmal Cyst 1: 1

Related Diseases

1.	Cysts

Experts

1.	Eiberg, Hans: 1 article (02/2005)
2.	Hansen, Claus: 1 article (02/2005)
3.	Hansen, Lars: 1 article (02/2005)
4.	Kjaer, Klaus Wilbrandt: 1 article (02/2005)
5.	Mohr, Jan: 1 article (02/2005)
6.	Teglbjaerg, Peter Stubbe: 1 article (02/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Trichilemmal Cyst 1:

1.	beta CateninIBA 02/15/2005 - "Mapping of hereditary trichilemmal cyst (TRICY1) to chromosome 3p24-p21.2 and exclusion of beta-CATENIN and MLH1."
2.	DNA (Deoxyribonucleic Acid)IBA 02/15/2005 - "In order to identify candidate genes for this trait we have ascertained a Danish family with 38 persons (11 affected), and carried out a genome wide scan with 580 DNA micro-satellite markers to identify the locus for a gene, which we termed TRICY1 (for trichilemmal cysts). "