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Otosclerosis 3

Also Known As:

OTSC3

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Otorhinolaryngologic Diseases: 203
- Ear Diseases: 261
  - Otosclerosis: 1435
    - Otosclerosis 3: 4

Related Diseases

1.	Otosclerosis
2.	Otitis Media
3.	Otosclerosis 2
4.	Otosclerosis 5

Experts

1.	Decat, Monique: 1 article (12/2009)
2.	Deveze, Arnaud: 1 article (12/2009)
3.	Dubreuil, Christian: 1 article (12/2009)
4.	Ibañez, Luis Garcia: 1 article (12/2009)
5.	Lavieille, Jean-Pierre: 1 article (12/2009)
6.	Lefebvre, Philippe P: 1 article (12/2009)
7.	Magnan, Jacques: 1 article (12/2009)
8.	Martin, Christian: 1 article (12/2009)
9.	Mom, Thierry: 1 article (12/2009)
10.	Richard, Céline: 1 article (12/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Otosclerosis 3:

1.	HLA-B Antigens (HLA-B)IBA 07/01/2002 - "The defined OTSC3 interval covers the HLA region, consistent with reported associations between HLA-A/HLA-B antigens and otosclerosis."
2.	HLA-A Antigens (HLA-A)IBA 07/01/2002 - "The defined OTSC3 interval covers the HLA region, consistent with reported associations between HLA-A/HLA-B antigens and otosclerosis."
3.	ElementsIBA 03/01/1975 - "This comparison indicated that: (1) with present techniques, the results of impedancemetry are only of a relative value in otosclerosis; it is thus necessary to asses the various connected anatomical elements in the middle ear with extreme rigor; (2) impedancemetry data have an absolute value in all disorders of the middle ear with closed eardrum associated with otosclerosis; (3) relative impedancemetry often gives informative results when it concurs with the other elements of clinical and audiometrical diagnosis; (4) impedancemetry data are a valuable element of early diagnosis of otosclerosis before the first audiometric expression, either by a lowering of compliance or, most of all, by appearance of an on-off effect (diphasic impedance change) or by disappearance of the stapedius reflex; (5) parallel or crossed paradoxical compliances are only apparently paradoxical and are usually the sign of either an early stapedo-vestibular fixation (before its audiometric expression) or an associated factor in the middle ear, both of which may have been unnoticed; (6) the problem of compliance value in otosclerosis will be solved only when the proper stapes frequency is found and when it is possible to test this frequency. "
4.	alpha2 Subunit Collagen Type IIBA 04/01/2006 - "Linkage analysis excluded linkage to the four known otosclerosis loci (OTSC1, OTSC2, OTSC3, and OTSC5), as well as to the COL1A1 and COL1A2 genes. "

Therapies and Procedures

1.	Operative Surgical Procedures 12/01/2009 - "All patients have multiple previous surgeries (>3 surgical procedures) for otosclerosis (3 patients) or chronic otitis media (8 patients), and in all cases, the stapes was not accessible due to obliteration by sclerotic tissue. "