Hypertension Resistant to Conventional Therapy

Hypertension that is associated with a variation in the NOS3 gene. Individuals with variations in NOS3 also are susceptible to coronary artery spasms. OMIM: 163729

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Cardiovascular Diseases: 91362
- Heart Diseases: 26014
  - Myocardial Ischemia: 25348
    - Coronary Disease: 27921
      - Coronary Vasospasm: 1630
        Hypertension Resistant to Conventional Therapy: 2
- Vascular Diseases: 15138
  - Hypertension: 147135
    - Hypertension Resistant to Conventional Therapy: 2
  - Myocardial Ischemia: 25348
    - Coronary Disease: 27921
      - Coronary Vasospasm: 1630
        Hypertension Resistant to Conventional Therapy: 2

Experts

1.	Edelman, Elazer R: 1 article (04/2015)
2.	Fuimaono, Kristine: 1 article (04/2015)
3.	Highsmith, Debby: 1 article (04/2015)
4.	Keating, John H: 1 article (04/2015)
5.	Mahfoud, Felix: 1 article (04/2015)
6.	Markham, Peter M: 1 article (04/2015)
7.	O'Fallon, Patrick: 1 article (04/2015)
8.	Spognardi, Anna-Maria: 1 article (04/2015)
9.	Stanley, James R L: 1 article (04/2015)
10.	Tzafriri, Abraham R: 1 article (04/2015)

Therapies and Procedures

1.	Denervation 02/01/2010 - "A proof-of-principle study in patients with hypertension resistant to conventional therapy has demonstrated that the procedure is safe and produces renal denervation with sustained lowering of arterial pressure." 04/29/2015 - "Renal denervation (RDN) is a treatment option for patients with hypertension resistant to conventional therapy. "