ISIS 4015

a phosphorothioate oligonucleotide complementary to herpes simplex virus type 1 (HSV-1) RNA

Also Known As:

ISIS-4015

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

1.	Retinitis 06/01/1997 - "ISIS 4015 showed very mild toxicity with no permanent retinal changes and very mild inflammation at doses of 10 microM; this dose was effective in ameliorating or preventing HSV-1 retinitis when injected 1 day and 1 week prior to virus inoculation. "
2.	Inflammation (Inflammations) 06/01/1997 - "ISIS 4015 showed very mild toxicity with no permanent retinal changes and very mild inflammation at doses of 10 microM; this dose was effective in ameliorating or preventing HSV-1 retinitis when injected 1 day and 1 week prior to virus inoculation. "

1.	Retinaldehyde (Retinal)