ISIS 3466

01/01/1993 - "Further study is needed to explore the tumor-inhibitory mechanisms of the effects of antisense oligodeoxynucleotide ISIS 3466."
11/11/1994 - "Apoptosis in human tumor cells following treatment with p120 antisense oligodeoxynucleotide ISIS 3466."
10/15/1993 - "Nucleolar and nuclear aberrations in human lox tumor cells following treatment with p120 antisense oligonucleotide ISIS-3466."
01/01/1994 - "The pharmacokinetics, tissue distribution, stability, and cellular uptake by LOX ascites tumor of p120 antisense phosphorothioate oligonucleotide, ISIS 3466, were studied in vivo. "
01/01/1993 - "Previous studies demonstrated that an antisense phosphorothioate oligodeoxynucleotide, ISIS 3466, to the human nucleolar p120 protein, markedly inhibited the growth of human tumor cell lines in vitro and inhibited the growth of the human LOX tumor in vivo in an i.p./i.p. "

01/01/1994 - "The pharmacokinetics, tissue distribution, stability, and cellular uptake by LOX ascites tumor of p120 antisense phosphorothioate oligonucleotide, ISIS 3466, were studied in vivo. "
02/01/1993 - "Preliminary in vivo studies on human LOX ascites tumor in nude mice showed marked inhibitory effects on tumor growth by the antisense oligonucleotide ISIS 3466 in the presence of DOTMA when treated on alternate days."