|1.||Zhang, Guang-Yi: 11 articles (12/2009 - 06/2003)|
|2.||Zhang, G-Y: 3 articles (09/2013 - 09/2008)|
|3.||Zimmermann, Pascale: 3 articles (09/2013 - 07/2005)|
|4.||Pei, Dong-Sheng: 3 articles (12/2009 - 08/2004)|
|5.||Sun, Ya-Feng: 3 articles (12/2009 - 08/2004)|
|6.||Hou, Xiao-Yu: 2 articles (09/2012 - 06/2003)|
|7.||Tymianski, Michael: 2 articles (03/2012 - 10/2002)|
|8.||Yu, Hong-Min: 2 articles (12/2009 - 10/2007)|
|9.||Zong, Yan-Yan: 2 articles (08/2009 - 06/2003)|
|10.||Gurd, James W: 2 articles (07/2009 - 10/2002)|
|1.||Transient Ischemic Attack
07/15/2013 - "In the present study, we investigated chronological change in the immunoreactivity of PSD-95, a kind of postsynaptic density protein, in the hippocampus proper (CA1-3 regions) after 5 min of transient cerebral ischemia in gerbils. "
10/22/2007 - "In this study, we investigated the interactions between synapse adhesion molecules neurexin, neuroligin1, neuroligin2 and postsynaptic density protein 95 (PSD-95) in transient cerebral ischemia and possible regulatory mechanism of these interactions. "
08/26/2004 - "Postsynaptic density protein 95 antisense oligodeoxynucleotides inhibits the activation of MLK3 and JNK3 via the GluR6.PSD-95.MLK3 signaling module after transient cerebral ischemia in rat hippocampus."
08/28/2009 - "In our previous studies, Tat-GluR6-9c (a glutamate receptor 6 C-terminus peptide fused the TAT protein transduction sequence) not only inhibited the activation of MLK3 (mixed lineage kinase 3) and JNK (c-Jun N-terminal kinase) via the GluR6.PSD-95 (postsynaptic density protein 95).MLK3 signaling module but also diminished neuronal death induced by kainic acid or transient cerebral ischemia in rat hippocampus. "
|2.||Brain Ischemia (Cerebral Ischemia)
09/17/2013 - "Global cerebral ischemia/reperfusion promoted the binding between neuronal nitric oxide synthase (nNOS) and postsynaptic density protein 95 that has been reported to activate nNOS, and GSNO inhibited the post-ischemic nNOS activation and NO release. "
09/01/2012 - "Previously, we reported that brain ischemia promotes the phosphorylation of postsynaptic density protein 95 (PSD-95) at tyrosine 523 (Y523), which is associated with postsynaptic mechanisms of excitotoxicity. "
08/01/2004 - "In this study, we examined the time-course and the effect of lithium on Tyr-402 phosphorylation of Pyk2 and Tyr-416 phosphorylation of Src as well as the association of Pyk2 and NMDA receptor subunit 2A (NR2A) mediated by postsynaptic density protein 95 kDa (PSD-95) in the condition of cerebral ischemia, which was induced by occlusion of the four vessels in Sprague-Dawley rats. "
12/01/2009 - "Our previous researches have shown that cerebral ischemia/reperfusion could facilitate the assembly of GluR6 and postsynaptic density protein 95(PSD95) as well as mixed lineage kinase 3(MLK3) and further induce the activation of c-Jun NH2-terminal kinase 3(JNK3), leading to neuronal death of hippocampal CA1. "
09/09/2008 - "Moreover, treatment with sodium nitroprusside (SNP), an exogenous NO donor, increases the S-nitrosylation and phosphorylation of nNOS, leading to the attenuation of the increased S-nitrosylation of GluR6 and the assembling of GluR6* postsynaptic density protein 95 (PSD95)* mixed lineage kinase 3 (MLK3) signaling module induced by cerebral ischemia-reperfusion. "
|3.||Major Depressive Disorder (Major Depressive Disorders)
08/15/2011 - "Our postmortem studies indicate robust deficits in prominent postsynaptic proteins including N-methyl-d-aspartate (NMDA) receptor subunits (NR2A, NR2B), metabotropic glutamate receptor subtype 5 (mGluR5) and postsynaptic density protein 95kDa (PSD-95) in the PFC in major depressive disorder (MDD). "
09/01/2013 - "Postsynaptic density protein, Discs-large, Zona occludens (PDZ) domains play important roles in the assembly of various signaling complexes. "
10/31/2007 - "The PDZ (postsynaptic density-95/Discs large/zona occludens 1)-binding domain at the C terminal, named as the T site, interacts with several postsynaptic density proteins. "
10/01/2015 - "Of the many GPCR-interacting proteins, postsynaptic density protein of 95 kilodaltons, disc large, zona occludens-1 (PDZ) domain-containing proteins appear most abundant and have similarly been implicated in disease mechanisms. "
02/21/2008 - "The Microtubule-Associated Serine/Threonine Kinase family (MAST1-4, and MAST-like) is characterised by the presence of a serine/threonine kinase domain and a postsynaptic density protein-95/discs large/zona occludens-1 domain (PDZ). "
07/20/2005 - "PDZ (Postsynaptic density protein, Disc large, Zona occludens) domains are protein-protein interaction modules that predominate in submembranous scaffolding proteins. "
|5.||Schizophrenia (Dementia Praecox)
01/06/2016 - "We have recently reported that protein levels of FRMPD4, a multiscaffolding protein that modulates both Homer1 and postsynaptic density protein 95 activity, is altered in the schizophrenia postmortem brain, in regions involved in cognition. "
02/01/2014 - "Glutamatergic postsynaptic density protein dysfunctions in synaptic plasticity and dendritic spines morphology: relevance to schizophrenia and other behavioral disorders pathophysiology, and implications for novel therapeutic approaches."
06/01/2009 - "In mice, reduced NMDAR expression leads to behaviors analogous to symptoms of schizophrenia, but reports of animals with mutations in core postsynaptic density proteins having similar a phenotype have yet to be reported. "
06/01/2015 - "Synaptic protein co-expression was significantly decreased in schizophrenia with the exception of a small group of postsynaptic density proteins, whose co-expression increased and inversely correlated with spine density in schizophrenia subjects. "
07/01/2004 - "In the present work, we observed increased expression of NMDA NR2B subunit transcripts, and decreased expression of all three associated postsynaptic density protein transcripts in schizophrenia. "
|2.||Proteins (Proteins, Gene)
|4.||mitogen-activated protein kinase kinase kinase 11
|5.||Glutamate Receptors (Glutamate Receptor)
|6.||Protein-Tyrosine Kinases (Tyrosine Kinase)
|8.||JNK Mitogen-Activated Protein Kinases
|9.||Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)
|10.||Protein Tyrosine Phosphatases