pipecolic acid

RN given refers to cpd without isomeric designation
Also Known As:
L-pipecolic acid; homopipecolic acid; pipecolic acid hydrochloride, (+-)-isomer; pipecolic acid, (+,-)-isomer; pipecolic acid, (R)-isomer; pipecolic acid, (S)-isomer; pipecolic acid, 14C-labeled cpd, (+,-)-isomer; pipecolic acid, ion (1-); pipecolic acid, ion(1-), (+,-)-isomer; pipecolic acid, ion(1-), (S)-isomer; pipecolic acid, monopotassium salt; 2-piperidinecarboxylic acid
Networked: 66 relevant articles (1 outcomes, 11 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Gospe, Sidney M: 3 articles (04/2011 - 04/2006)
2. Kaczmarek, Piotr: 2 articles (10/2012 - 06/2011)
3. Keay, Susan: 2 articles (10/2012 - 06/2011)
4. Zhang, Chen-Ou: 2 articles (10/2012 - 06/2011)
5. Plecko, B: 2 articles (06/2005 - 01/2005)
6. Struys, E: 2 articles (06/2005 - 01/2005)
7. Jakobs, C: 2 articles (06/2005 - 01/2005)
8. Lanza, Elaine: 1 article (04/2015)
9. Hartman, Terryl J: 1 article (04/2015)
10. Murphy, Gwen: 1 article (04/2015)

Related Diseases

1. Zellweger Syndrome (Zellweger's Syndrome)
2. Peroxisomal Disorders (Peroxisomal Disorder)
3. Liver Diseases (Liver Disease)
4. Seizures (Seizure)
5. Refsum Disease (Refsum's Disease)
02/01/1988 - "Our data suggest that some patients with the infantile form of Refsum disease may show some clinical benefit from dietary management and this is reflected biochemically by decreases in the plasma levels of phytanic acid and pipecolic acid."
08/01/1986 - "In recent years a number of biochemical abnormalities have been described in patients with the infantile form of Refsum disease, including the accumulation of very long chain fatty acids, trihydroxycoprostanoic acid and pipecolic acid. "
12/01/1984 - "The plasma of patients with the infantile but not the adult form of Refsum's disease contains increased amounts of pipecolic acid and of at least two abnormal bile acids, one of which has been identified as 3 alpha, 7 alpha, 12 alpha trihydroxy-5 beta-cholestan-26-oic acid. "
10/01/1995 - "We present here genome wide linkage analysis of an atypical Refsum disease family where L-pipecolic acid level in blood was also increased, suggesting that the patients suffer from a new peroxisomal disorder intermediate between ARD and Infantile Refsum Disease (IRD, a peroxisomal deficiency disease). "
04/01/1988 - "In this study we carried out a detailed investigation into different peroxisomal functions in classical Refsum's disease by analyses of plasma (very long chain fatty acids, di- and trihydroxycoprostanoic acid and pipecolic acid) and cultured skin fibroblasts from the patients (de novo plasmalogen biosynthesis, very long chain fatty acid oxidation and amount of particle-bound catalase). "

Related Drugs and Biologics

1. pipecolic acid
2. Fatty Acids (Saturated Fatty Acids)
3. Pyridoxine (Pyridoxin)
4. Phytanic Acid
5. Uric Acid (Urate)
6. Serotonin (5 Hydroxytryptamine)
7. Pyridoxal Phosphate (Pyridoxal 5 Phosphate)
8. Oxidoreductases
9. Lipoproteins (Lipoprotein)
10. Catalase