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poly(dG)
Also Known As:
poly dG; polydeoxyguanylic acid
Networked:
6
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Nucleic Acids, Nucleotides, and Nucleosides: 1
Nucleotides: 15763
Polynucleotides: 218
Polyribonucleotides: 23
Poly G: 32
poly(dG): 6
Related Diseases
1.
Virus Diseases (Viral Diseases)
01/01/1976 - "
Three kinds of DNA polymerases from spleen were not inhibited by bleomycin, but the fourth enzyme, which was induced in the spleen by virus infection, was inhibited by the antibiotic, when poly-d(AT) and poly-dG with dC were used as template.
"
2.
Rabies (Hydrophobia)
11/08/1984 - "
We first altered the rabies glycoprotein cDNA by site-directed mutagenesis and removed the poly(dG) tail.
"
3.
Systemic Lupus Erythematosus (Libman-Sacks Disease)
05/01/1985 - "
Immunochemical properties of monoclonal autoantibodies to single stranded DNA (ssDNA), which were derived from systemic lupus erythematosus (SLE) prone mice and were specific for poly(dG), were studied using a hapten inhibition assay with oligo- and mononucleotides.
"
4.
Hypergammaglobulinemia (Hyperimmunoglobulinemia)
06/01/1984 - "
While hypergammaglobulinemia, rheumatoid factor (RF) and elevated Clq binding were significantly more frequent among the anti-Ro positive group there was no increase in the frequency of anti-dsDNA antibody measured by the Farr assay or antibodies to ssDNA, dsDNA, poly dG .
"
5.
Chromosome Aberrations (Chromosome Abnormalities)
09/01/1988 - "
Cells transfected with the vector alone (and resistant to 0.02 or 1.0 microM MTX) or with a poly(dG-dT) insert (and resistant to 0.05 or 1.0 microM MTX) showed little change in chromosome aberrations or sister chromatid exchange frequencies.
"
Related Drugs and Biologics
1.
Complementary DNA (cDNA)
2.
Enzymes
3.
DNA-Directed DNA Polymerase (Polymerases, DNA)
4.
Viral RNA
5.
DNA-Directed RNA Polymerases (RNA Polymerase)
6.
Rheumatoid Factor
7.
Poly T
8.
Poly A
9.
Haptens
10.
Glycoproteins (Glycoprotein)