C 541

RN & NM refer to HCl; structure

Also Known As:

1-nitro-10-(dimethylaminoethyl)-9-acridone.HCl; C-541; 10-(2-(dimethylamino)ethyl)-1-nitro-9(10H)-acridinone, monohydrochloride

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

1.	46,XY Disorder of Sex Development (Male Pseudohermaphroditism) 01/01/2018 - "We identified a homozygous ESR2 variant, c.541_543del p.(Asn181del), located in the highly conserved DNA-binding domain of ER-β, in an individual with syndromic 46,XY DSD. "
2.	Retinitis Pigmentosa (Pigmentary Retinopathy) 01/01/2018 - "The c.541-15T>G mutation in LRAT results in aberrant splicing and is therefore predicted to be causal for the early onset retinitis pigmentosa in this family. "
3.	Neoplasms (Cancer) 12/01/2018 - "IHC staining of tumors from the c.343C>T and c.541-2A>G carriers showed positive expression of SDHB. "

1.	DNA (Deoxyribonucleic Acid)