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5-fluoroisocytosine
prodrug of 5-fluorocytosine
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyrimidines: 510
Pyrimidinones: 71
Cytosine: 1880
Flucytosine: 1032
5-fluoroisocytosine: 1
Related Diseases
1.
Neoplasms (Cancer)
09/15/2023 - "
Non-natural nucleobase isocytosine (IC) is the isomer of cytosine; its chemical derivate 5-fluoroisocytosine (5-FIC) together with the isocytosine-specific deaminase (ICD) VCZ was suggested to be potential practical enzyme/prodrug pair for cancer therapy through gene-directed enzyme-prodrug therapy (GDEPT) method.
"
Related Drugs and Biologics
1.
Prodrugs
2.
Enzymes
3.
Cytosine
4.
isocytosine
Related Therapies and Procedures
1.
Therapeutics