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NRL972
a fluorescent-labelled bile salt, an investigational marker of hepatic biliary transporter function
Also Known As:
fluorescein lisicol
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Spiro Compounds: 2
Fluoresceins: 2
NRL972: 1
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
3-Ring Heterocyclic Compounds
Xanthenes: 65
Fluoresceins: 2
NRL972: 1
Polycyclic Compounds: 6
Spiro Compounds: 2
Fluoresceins: 2
NRL972: 1
Experts
1.
Deliyska, Boriana
: 1 article (07/2015)
2.
Gatchev, Emil
: 1 article (07/2015)
3.
de Mey, Christian
: 1 article (07/2015)
Related Diseases
1.
Renal Insufficiency (Renal Failure)
07/01/2015 - "
Renal insufficiency does not impair the elimination of NRL972; instead, there is a trend of enhanced NRL972 disposition in patients with compromised renal function.
"
07/01/2015 - "
To investigate the pharmacokinetics (PK) of NRL972 in patients with severe (SRI: creatinine clearance (CLCr)<30 mL/min per 1.73 m2 body surface area (BSA)) and mild-to-moderate renal insufficiency (MRI: 30≤CLCr<80 mL/min) relative to matched controls (CON: CLCr≥90 mL/min).
"
07/01/2015 - "
Effects of renal insufficiency on the elimination of fluorescein lisicol (NRL972), an investigational marker of hepatic transporter function.
"
Related Drugs and Biologics
1.
NRL972
2.
Creatinine