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11-deoxy glycyrrhetinic acid

has antineoplastic activity; structure in first source

Also Known As:

11-DOGA; 11-deoxyglycyrrhetinic acid

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - Pentacyclic Triterpenes: 108
        Glycyrrhetinic Acid: 395
        11-deoxy glycyrrhetinic acid: 1

Experts

1.	Hu, Tianhui: 1 article (01/2014)
2.	Li, Juan: 1 article (01/2014)
3.	Lin, Dejian: 1 article (01/2014)
4.	Song, Gang: 1 article (01/2014)
5.	Zhang, Bing: 1 article (01/2014)
6.	Zhong, Wei: 1 article (01/2014)

Related Diseases

1.	Stomach Neoplasms (Stomach Cancer) 01/01/2014 - "Comparing with 11-DOGA, GA presents higher toxicity toward gastric cancer cells both in vivo and in vitro. " 01/01/2014 - "Firstly, we found that GA and 11-DOGA significantly inhibits the viabilities of gastric cancer cells in dose- and time-dependent manners. " 01/01/2014 - "Here, we report that the functional mechanisms of GA and 11-DOGA in gastric cancers, as well as the comparison between these two drugs' pharmacological potential. " 01/01/2014 - "Moreover, GA and 11-DOGA could effectively inhibit tumor formation of gastric cancer cells in nude mice. " 01/01/2014 - "Both GA and 11-DOGA induce gastric cancer cells apoptosis and cell cycle arrest in G2 phase by upregulation of p21 and downregulation of cdc2 and cyclin B1. "
2.	Neoplasms (Cancer) 01/01/2014 - "Moreover, GA and 11-DOGA could effectively inhibit tumor formation of gastric cancer cells in nude mice. "

Related Drugs and Biologics

1.	Cyclin B1
2.	Glycyrrhetinic Acid (Po 12)