Cyclin B1

07/10/2023 - "In addition, in vivo studies have confirmed that silencing CDCA8 could regulate CDK1/cyclin B1 signaling axis to inhibit the growth of HCC xenograft tumor. "
01/01/2022 - "Multiple studies report that cyclin B1 is upregulated in cancers and promotes cancer progression. "
12/05/2018 - "Our study provides a mechanism by which gastric tumor cells maintain their high proliferation rate via coordination of Aurora B and CREPT/RPRD1B on the expression of Cyclin B1. "
11/10/2017 - "Recently, several studies have reported that the expression of cyclin B1 may be associated with the prognosis of cancer. "
01/10/2017 - "Numerous studies have reported contradictory evidences of the correlation between cyclin B1 expression and prognosis in human solid tumors. "

09/01/2006 - "In this study, we evaluated the immunohistochemical expression of cyclin B1 in a series of 40 oral tongue squamous cell carcinomas and analyzed the findings in relation to both clinicopathological variables and the Ki-67 labeling index. "
03/01/2002 - "The aim of the present study was to elucidate the biological significance of cyclin B1 expression in squamous cell carcinoma (SCC) of the esophagus. "
09/06/2016 - "Forced expression of EF2 resulted in the enhancement of lung squamous carcinoma NCI-H520 cells growth through promotion of G2/M progression in cell cycle, activating Akt and Cdc2/Cyclin B1. "
01/01/2015 - "In conclusion, CDK1Tyr15, pCDK1Thr161, Cyclin B1 (total) and pCyclin B1Ser126 may be involved in progression of vulvar squamous cell carcinoma. "
01/01/2015 - "Therefore, we evaluated the statuses of CDK1Tyr15, pCDK1Thr161, Cyclin B1 (total) and pCyclin B1Ser126 in 297 cases of vulvar squamous cell carcinomas by immunohistochemistry. "

09/01/2007 - "Our studies demonstrate that primary human AML cells show aberrant cytoplasmic expression of cyclin B1 for a majority of patients and a specific humoral immune response was also detected for a subset of patients with untreated leukemia."
06/01/2016 - "Our results may reflect involvement of cyclin B1 in opposite processes - apoptosis induction and maintenance of cell viability in leukemia cells. "
10/01/2005 - "Expressions of cyclin B1 and p21cipl in adult acute leukemia and their correlation."
10/01/2003 - "To investigate the clinical significance of cyclin B1 expression in adult acute leukemia (AL) patients. "
10/01/2003 - "[The clinical significance of cyclin B1 expression in adult acute leukemia patients]."

03/01/2007 - "This study was to reveal the molecular mechanism of antisense cyclin B1 in tumorigenesis inhibition by comparative proteomic technique. "
03/01/2007 - "[Mechanism study of antisense cyclin B1 in tumorigenesis inhibition using proteomic technique]."
08/01/2023 - "The elevated Cyclin B1 expression contributes to various tumorigenesis and poor prognosis. "
01/01/2022 - "Furthermore, knockdown of RIOK1 could inhibit proliferation, migration, and invasion in NSCLC cells and tumorigenesis in vivo through AKT, Cyclin B1, MMP2, and EMT pathway. "
12/05/2018 - "We proposed that phosphorylation of CREPT/RPRD1B by Aurora B is required for promoting the transcription of Cyclin B1, which is critical for the regulation of gastric tumorigenesis. "

03/01/2006 - "There was significantly greater cyclin B1 expression in invasive cervical cancer than in normal cervical tissue (P = 0.019). "
03/01/2006 - "This study was undertaken to quantitatively detect cyclin B1 and D1 in cervical cancer. "
06/01/2022 - "Furthermore, RACGAP1 knockdown decreased the level of CDC2, p-CDC2, CDC25C, and Cyclin B1, inhibited proliferation and delayed cell cycle progression in cervical cancer cells. "
01/01/2020 - "Cyclin B1 (CCNB1) represents a hub gene during the development of cervical cancer. "
10/14/2010 - "We show here that depleting cyclin B1 stabilizes and reactivates p53 in papillomavirus-infected cervical cancer cell lines HeLa and CaSki. "