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human peptide deformylase

do not confuse wtih tumor differentiation factor, also known as PDF

Also Known As:

peptide deformylase, human; HsPDF protein, human; mitochondrial protein peptide deformylase, human

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Amidohydrolases: 43
      - human peptide deformylase: 4

Experts

1.	Choi, Yun-Seok: 1 article (04/2010)
2.	Han, Ji-Hoon: 1 article (04/2010)
3.	Jeon, Young Ho: 1 article (04/2010)
4.	Kim, Won-Je: 1 article (04/2010)
5.	Lee, Bong-Jin: 1 article (04/2010)
6.	Lee, Seung Kyu: 1 article (04/2010)
7.	Ryu, Kyoung-Seok: 1 article (04/2010)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2023 - "Human peptide deformylase (hsPDF) has been found overexpressed in many cancer cells and its inhibitors exhibit antitumor activity. " 01/01/2023 - "A new inhibitor of human peptide deformylase suppresses cell proliferation and induces cell apoptosis and autophagy in cancers." 04/01/2010 - "Human peptide deformylase (hPDF), located in the mitochondria, has recently become a promising target for anti-cancer therapy. " 12/01/2022 - "Actinonin, a human peptide deformylase inhibitor, has demonstrated anti-cancerous properties in various leukemias and solid cancer types. "
2.	Leukemia 12/01/2022 - "Actinonin, a human peptide deformylase inhibitor, has demonstrated anti-cancerous properties in various leukemias and solid cancer types. "
3.	Glioblastoma (Glioblastoma Multiforme) 11/15/2022 - "Inhibition of human peptide deformylase by actinonin sensitizes glioblastoma cells to temozolomide chemotherapy."

Related Drugs and Biologics

1.	actinonin
2.	Temozolomide (Temodar)

Related Therapies and Procedures

1.	Therapeutics
2.	Drug Therapy (Chemotherapy)