Ataxin-2

A Poly(A) RNA-binding protein that negatively regulates EGFR ENDOCYTOSIS. An increased risk for developing AMYOTROPHIC LATERAL SCLEROSIS 13 is observed in patients who have more than 23 CAG repeats in the ATXN2 gene coding sequence. Larger CAG expansions in the ATXN2 gene occur in SPINOCEREBELLAR ATAXIA 2 patients.

Also Known As:

ATXN2 Protein; Ataxin-2 Protein; Atx-2 Protein; SCA2 Protein; Spinocerebellar Ataxia Type 2 Protein; Ataxin 2; Ataxin 2 Protein; Atx 2 Protein; Protein, ATXN2; Protein, Ataxin-2; Protein, Atx-2; Protein, SCA2

Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Carrier Proteins: 13306
    - RNA-Binding Proteins: 3439
      - Poly(A)-Binding Proteins: 86
        Ataxin-2: 162
  - Nuclear Proteins: 2740
    - Ataxins: 30
      - Ataxin-2: 162
  - Nucleoproteins: 1892
    - RNA-Binding Proteins: 3439
      - Poly(A)-Binding Proteins: 86
        Ataxin-2: 162
  - Nerve Tissue Proteins: 3
    - Ataxins: 30
      - Ataxin-2: 162

mouse Atxn2 protein

Bio-Agent Context: Research Results