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ethyl 2- amino- 3- (4- (2- amino- 6- (2,2,2- trifluoro- 1- (3'- fluorobiphenyl- 4- yl)ethoxy)pyrimidin- 4- yl)phenyl)propanoic acid

LP-615819 is the racemic mixture; LP-920540 is the (2S)-isomer; a tryptophan hydroxylase inhibitor; structure in first source

Also Known As:

LP-615819; LP-920540

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Essential Amino Acids: 1152
    - Phenylalanine: 4090
      - ethyl 2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(3'-fluorobiphenyl-4-yl)ethoxy)pyrimidin-4-yl)phenyl)propanoic acid: 1
  - Cyclic Amino Acids: 3
    - Aromatic Amino Acids: 467
      - Phenylalanine: 4090
        ethyl 2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(3'-fluorobiphenyl-4-yl)ethoxy)pyrimidin-4-yl)phenyl)propanoic acid: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - ethyl 2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(3'-fluorobiphenyl-4-yl)ethoxy)pyrimidin-4-yl)phenyl)propanoic acid: 1

Experts

1.	Diacou, Alexander: 1 article (06/2014)
2.	Gershon, Michael D: 1 article (06/2014)
3.	Jhaver, Kanchan G: 1 article (06/2014)
4.	Li, Zhishan: 1 article (06/2014)
5.	Margolis, Kara Gross: 1 article (06/2014)
6.	Oravecz, Tamas: 1 article (06/2014)
7.	Stevanovic, Korey: 1 article (06/2014)
8.	Yang, Qi Melissa: 1 article (06/2014)
9.	Zambrowicz, Brian: 1 article (06/2014)

Related Diseases

1.	Inflammation (Inflammations) 06/01/2014 - "In contrast, oral LP-920540 and LX1032 reduced the severity of TNBS-induced colitis; the expression of 24% of 84 genes encoding inflammation-related cytokines and chemokines was lowered at least fourfold and the reduced expression of 17% was statistically significant. "
2.	Colitis 06/01/2014 - "In contrast, oral LP-920540 and LX1032 reduced the severity of TNBS-induced colitis; the expression of 24% of 84 genes encoding inflammation-related cytokines and chemokines was lowered at least fourfold and the reduced expression of 17% was statistically significant. "

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