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5- fluoro- 2- (2- (1- (4- fluorophenyl)- 5- hydroxy- 4a- methyl- 1,4,4a,5,6,7- hexahydrocyclopenta(f)indazol- 5- yl)ethyl)benzamide

a glucocorticoid receptor modulator with anti-inflammatory activity; structure in first source

Also Known As:

MK-5932

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrazoles: 61
      - Indazoles: 179
        5-fluoro-2-(2-(1-(4-fluorophenyl)-5-hydroxy-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta(f)indazol-5-yl)ethyl)benzamide: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indazoles: 179
      - 5-fluoro-2-(2-(1-(4-fluorophenyl)-5-hydroxy-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta(f)indazol-5-yl)ethyl)benzamide: 2

Experts

1.	Bai, Chang: 2 articles (02/2014 - 12/2011)
2.	Brandish, Philip E: 2 articles (02/2014 - 12/2011)
3.	Bungard, Christopher J: 2 articles (02/2014 - 12/2011)
4.	Hershey, James C: 2 articles (02/2014 - 12/2011)
5.	Meissner, Robert S: 2 articles (02/2014 - 12/2011)
6.	Schmidt, Azriel: 2 articles (02/2014 - 12/2011)
7.	Thompson, Charles D: 2 articles (02/2014 - 12/2011)
8.	Anderson, Kenneth: 1 article (02/2014)
9.	Baltus, Gretchen A: 1 article (02/2014)
10.	Bunting, Patricia: 1 article (02/2014)

Related Diseases

1.	Contact Dermatitis (Eczema, Contact) 02/05/2014 - "MK-5932 was anti-inflammatory in a rat contact dermatitis model, but was differentiated from 6-methylprednisolone by a lack of elevation of fasting insulin or glucose levels after 7 days of dosing, even at high exposure levels. "
2.	Dermatitis 12/15/2011 - "Orally administered MK-5932 displayed anti-inflammatory efficacy in a Rat Oxazolone-induced chronic dermatitis model, while sparing plasma insulin."
3.	Experimental Arthritis 02/05/2014 - "MK-5932 was also anti-inflammatory in the rat collagen-induced arthritis and adjuvant-induced arthritis models. "
4.	Arthritis (Polyarthritis) 02/05/2014 - "MK-5932 was also anti-inflammatory in the rat collagen-induced arthritis and adjuvant-induced arthritis models. "

Related Drugs and Biologics

1.	Insulin (Novolin)
2.	Oxazolone
3.	Methylprednisolone
4.	Glucose (Dextrose)