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Bharat B Aggarwal Selected Research

Curcumin

10/2010Cyclodextrin-complexed curcumin exhibits anti-inflammatory and antiproliferative activities superior to those of curcumin through higher cellular uptake.
8/2010Targeting inflammation-induced obesity and metabolic diseases by curcumin and other nutraceuticals.
8/2010Curcumin selectively induces apoptosis in cutaneous T-cell lymphoma cell lines and patients' PBMCs: potential role for STAT-3 and NF-kappaB signaling.
1/2010Curcumin potentiates the antitumor effects of gemcitabine in an orthotopic model of human bladder cancer through suppression of proliferative and angiogenic biomarkers.
12/2009Curcumin potentiates the antitumor effects of Bacillus Calmette-Guerin against bladder cancer through the downregulation of NF-kappaB and upregulation of TRAIL receptors.
11/2009Curcumin inhibits COPD-like airway inflammation and lung cancer progression in mice.
11/2009Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model.
10/2009Curcumin modulates the radiosensitivity of colorectal cancer cells by suppressing constitutive and inducible NF-kappaB activity.
9/2009Curcumin and cancer cells: how many ways can curry kill tumor cells selectively?
4/2009Curcumin circumvents chemoresistance in vitro and potentiates the effect of thalidomide and bortezomib against human multiple myeloma in nude mice model.
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Bharat B Aggarwal Research Topics

Disease

154Neoplasms (Cancer)
10/2010 - 01/2002
43Inflammation
08/2010 - 03/2002
40Neoplasm Metastasis (Metastasis)
08/2010 - 09/2002
17Multiple Myeloma
07/2010 - 02/2003
13Leukemia
05/2010 - 08/2003
13Breast Neoplasms (Breast Cancer)
04/2010 - 09/2002
11Arthritis (Polyarthritis)
01/2009 - 07/2004
9Pancreatic Neoplasms (Pancreatic Cancer)
07/2010 - 09/2006
7Chronic Disease (Chronic Diseases)
05/2010 - 01/2007
7Rheumatoid Arthritis
01/2009 - 09/2003
7Asthma (Bronchial Asthma)
11/2008 - 07/2004
7Atherosclerosis (Atheroma)
02/2008 - 07/2004
7Carcinoma (Carcinomatosis)
06/2007 - 09/2004
6Myeloid Leukemia (Leukemia, Myelocytic)
08/2010 - 12/2002
6Obesity
08/2010 - 11/2004
6Prostatic Neoplasms (Prostate Cancer)
03/2010 - 12/2002
6Bone Resorption
02/2009 - 09/2003
6Osteoporosis
02/2009 - 12/2004
6Melanoma (Melanoma, Malignant)
11/2008 - 09/2004
6Acquired Immunodeficiency Syndrome (AIDS)
03/2008 - 01/2003
6Alzheimer Disease (Alzheimer's Disease)
02/2008 - 12/2004
6Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
07/2005 - 01/2002
5Squamous Cell Carcinoma (Epidermoid Carcinoma)
08/2008 - 12/2002
4Hyperlipidemias (Hyperlipidemia)
08/2010 - 11/2004
4Lung Neoplasms (Lung Cancer)
11/2009 - 12/2006
4Adenocarcinoma
11/2009 - 07/2004
4Psoriasis (Pustulosis Palmaris et Plantaris)
01/2009 - 12/2004
4Cardiovascular Diseases (Cardiovascular Disease)
01/2009 - 11/2005
4Necrosis
01/2009 - 07/2002
4Crohn Disease (Crohn's Disease)
11/2007 - 12/2004
3Urinary Bladder Neoplasms (Bladder Cancer)
01/2010 - 03/2007
3Colorectal Neoplasms (Colorectal Cancer)
11/2009 - 04/2008
3Colonic Neoplasms (Colon Cancer)
08/2009 - 02/2006
3Anoxia (Hypoxia)
08/2009 - 01/2007
3Infection
01/2009 - 07/2004
3Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2009 - 07/2004
3Ovarian Neoplasms (Ovarian Cancer)
08/2008 - 03/2004
3Osteoarthritis
06/2007 - 11/2004
3Hypersensitivity (Allergy)
01/2007 - 12/2004
3Septic Shock (Toxic Shock Syndrome)
12/2004 - 09/2003
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
08/2004 - 07/2003
2Metabolic Diseases (Metabolic Disease)
08/2010 - 02/2009
2Insulin Resistance
08/2010 - 06/2008
2Hypertension (High Blood Pressure)
05/2010 - 06/2006

Drug/Important Bio-Agent (IBA)

111NF-kappa B (NF-kB)IBA
08/2010 - 03/2002
48CurcuminIBA
10/2010 - 01/2002
44Transcription Factors (Transcription Factor)IBA
08/2010 - 09/2002
24Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2010 - 02/2002
22Cyclin D1IBA
08/2010 - 12/2002
16Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
08/2010 - 11/2004
12Cyclooxygenase 2 (Cyclooxygenase-2)IBA
12/2009 - 09/2002
11CytokinesIBA
08/2010 - 10/2003
11Phosphotransferases (Kinase)IBA
01/2010 - 08/2004
10Proteins (Proteins, Gene)IBA
08/2010 - 01/2002
10resveratrolIBA
07/2010 - 09/2002
10I-kappa B KinaseIBA
04/2010 - 02/2003
8SmokeIBA
11/2009 - 09/2002
8CarcinogensIBA
11/2007 - 09/2002
7DNA (Deoxyribonucleic Acid)IBA
05/2010 - 04/2004
6gemcitabineFDA LinkGeneric
07/2010 - 11/2004
6Protein Kinases (Protein Kinase)IBA
09/2009 - 08/2005
6Transcription Factor AP-1 (Transcription Factor AP 1)IBA
08/2009 - 12/2002
5zerumboneIBA
08/2009 - 10/2005
5Interleukin-6 (Interleukin 6)IBA
08/2009 - 10/2003
5Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
07/2009 - 07/2004
4Matrix Metalloproteinase 9 (Gelatinase B)IBA
05/2010 - 07/2004
4NF-kappaB inhibitor alphaIBA
04/2010 - 05/2004
4Biological Markers (Surrogate Marker)IBA
01/2010 - 06/2006
4Thalidomide (Thalomid)FDA Link
04/2009 - 03/2002
4bortezomib (Velcade)FDA Link
04/2009 - 05/2004
4Receptor Activator of Nuclear Factor-kappa B (TRANCE-R)IBA
02/2009 - 01/2006
4pregna-4,17-diene-3,16-dione (guggulsterone)IBA
11/2008 - 11/2004
4Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
11/2007 - 02/2006
3thymoquinoneIBA
06/2010 - 07/2008
3Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
05/2010 - 01/2006
3tripterineIBA
04/2010 - 04/2007
3Caspase 8 (Caspase-8)IBA
04/2010 - 09/2009
3ChemokinesIBA
08/2009 - 01/2003
3Dexamethasone (Maxidex)FDA LinkGeneric
04/2009 - 12/2004
3Doxorubicin (Adriamycin)FDA LinkGeneric
04/2009 - 12/2005
3EnzymesIBA
01/2009 - 06/2006
3Methylcellulose (BFL)IBA
11/2008 - 11/2004
3Cyclin EIBA
08/2008 - 02/2006
3Proteasome Endopeptidase Complex (Proteasome)IBA
10/2007 - 05/2004
3JNK Mitogen-Activated Protein KinasesIBA
06/2007 - 01/2003
3celecoxib (Celebrex)FDA Link
12/2004 - 07/2004
2TNF Receptor-Associated Factor 1IBA
08/2010 - 01/2006
2Non-Receptor Type 6 Protein Tyrosine PhosphataseIBA
07/2010 - 01/2009
2betulinic acidIBA
07/2010 - 09/2003
2indole-3-carbinolIBA
06/2010 - 07/2005
2Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
05/2010 - 07/2008
2TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA
04/2010 - 12/2009
270-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA
03/2010 - 07/2007
2InterleukinsIBA
01/2010 - 03/2006
2plumbaginIBA
01/2010 - 06/2006
2Interleukin-1 (Interleukin 1)IBA
08/2009 - 10/2004
2acetyl-11-ketoboswellic acidIBA
07/2009 - 03/2006

Therapy/Procedure

11Heterologous Transplantation (Xenotransplantation)
05/2010 - 10/2005
10Drug Therapy (Chemotherapy)
08/2008 - 11/2003
6Chemoprevention
06/2010 - 11/2002