Abstract | BACKGROUND: The prognosis of infants with prolonged neonatal jaundice is dependent on early diagnosis because of the need for prompt surgical management of biliary atresia. OBJECTIVE: MATERIALS AND METHODS: A retrospective study was undertaken of 58 patients with unexplained prolonged neonatal jaundice. Sixty-eight scans were reviewed. RESULTS: CONCLUSIONS:
Mebrofenin scintigraphy is accurate in confirming the presence of a choledochal cyst and in refuting the diagnosis of EHBA. While histology and scintigraphy are each 100 % sensitive for the diagnosis of EHBA, neither, individually, is accurate and the investigation of prolonged neonatal jaundice requires a multi-modality imaging strategy.
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Authors | K Johnson, H M Alton, S Chapman |
Journal | Pediatric radiology
(Pediatr Radiol)
Vol. 28
Issue 12
Pg. 937-41
(Dec 1998)
ISSN: 0301-0449 [Print] Germany |
PMID | 9880637
(Publication Type: Journal Article)
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Chemical References |
- Aniline Compounds
- Imino Acids
- Organotechnetium Compounds
- Radiopharmaceuticals
- technetium Tc 99m mebrofenin
- Glycine
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Topics |
- Aniline Compounds
- Biliary Atresia
(complications, diagnostic imaging)
- Choledochal Cyst
(complications, diagnostic imaging)
- Glycine
- Hepatitis
(complications, congenital, diagnostic imaging)
- Humans
- Imino Acids
- Infant, Newborn
- Jaundice, Neonatal
(diagnostic imaging, etiology)
- Liver
(diagnostic imaging)
- Organotechnetium Compounds
- Radionuclide Imaging
- Radiopharmaceuticals
- Retrospective Studies
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