Abstract | OBJECTIVE: The purpose of this study was to evaluate the usefulness of a Kampo medicine (Sai-boku-to) for treatment of patients with glossodynia. STUDY DESIGN: Sai-boku-to or an antianxiety drug ( diazepam) with vitamin B complex was administered orally for 3 months to each of 200 patients with glossodynia. Clinical examination evaluated the following subjective symptoms: pain, burning sensation, and discomfort. Effectiveness was evaluated as follows: "markedly effective," all 3 symptoms disappeared; "effective," pain improved; "ineffective," no improvement in pain. RESULTS: The effective rates were 70% after 1 month, 85% after 2 months, and 92% after 3 months of administration of Sai-boku-to (the Kampo group) and 74% after 1 month, 71% after 2 months, and 69% after 3 months of administration of the antianxiety drug with vitamin B complex (the control group). No significant side effect was noted in the Kampo group, but sleepiness was recorded in 33 cases in the control group. CONCLUSIONS: The results indicate that Sai-boku-to may be a clinically useful medicine for the long-term treatment of patients with glossodynia.
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Authors | K Bessho, Y Okubo, S Hori, K Murakami, T Iizuka |
Journal | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
(Oral Surg Oral Med Oral Pathol Oral Radiol Endod)
Vol. 86
Issue 6
Pg. 682-6
(Dec 1998)
ISSN: 1079-2104 [Print] United States |
PMID | 9868725
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Anti-Anxiety Agents
- Drugs, Chinese Herbal
- Vitamin B Complex
- Diazepam
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Analysis of Variance
- Anti-Anxiety Agents
(therapeutic use)
- Chi-Square Distribution
- Diazepam
(therapeutic use)
- Drugs, Chinese Herbal
(therapeutic use)
- Female
- Glossalgia
(drug therapy)
- Humans
- Male
- Medicine, Chinese Traditional
- Middle Aged
- Outcome Assessment, Health Care
- Vitamin B Complex
(therapeutic use)
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