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Effectiveness of kampo medicine (sai-boku-to) in treatment of patients with glossodynia.

AbstractOBJECTIVE:
The purpose of this study was to evaluate the usefulness of a Kampo medicine (Sai-boku-to) for treatment of patients with glossodynia.
STUDY DESIGN:
Sai-boku-to or an antianxiety drug (diazepam) with vitamin B complex was administered orally for 3 months to each of 200 patients with glossodynia. Clinical examination evaluated the following subjective symptoms: pain, burning sensation, and discomfort. Effectiveness was evaluated as follows: "markedly effective," all 3 symptoms disappeared; "effective," pain improved; "ineffective," no improvement in pain.
RESULTS:
The effective rates were 70% after 1 month, 85% after 2 months, and 92% after 3 months of administration of Sai-boku-to (the Kampo group) and 74% after 1 month, 71% after 2 months, and 69% after 3 months of administration of the antianxiety drug with vitamin B complex (the control group). No significant side effect was noted in the Kampo group, but sleepiness was recorded in 33 cases in the control group.
CONCLUSIONS:
The results indicate that Sai-boku-to may be a clinically useful medicine for the long-term treatment of patients with glossodynia.
AuthorsK Bessho, Y Okubo, S Hori, K Murakami, T Iizuka
JournalOral surgery, oral medicine, oral pathology, oral radiology, and endodontics (Oral Surg Oral Med Oral Pathol Oral Radiol Endod) Vol. 86 Issue 6 Pg. 682-6 (Dec 1998) ISSN: 1079-2104 [Print] United States
PMID9868725 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
Chemical References
  • Anti-Anxiety Agents
  • Drugs, Chinese Herbal
  • Vitamin B Complex
  • Diazepam
Topics
  • Adult
  • Aged
  • Aged, 80 and over
  • Analysis of Variance
  • Anti-Anxiety Agents (therapeutic use)
  • Chi-Square Distribution
  • Diazepam (therapeutic use)
  • Drugs, Chinese Herbal (therapeutic use)
  • Female
  • Glossalgia (drug therapy)
  • Humans
  • Male
  • Medicine, Chinese Traditional
  • Middle Aged
  • Outcome Assessment, Health Care
  • Vitamin B Complex (therapeutic use)

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