Abstract |
The study was carried out in 178 women without grave obstetrical or extragenital diseases. In group 1 labor pain was relieved by prolonged epidural anesthesia with 2% lidocaine solution (2-2.5 mg/kg), in group 2 prolonged epidural anesthesia with 1% lidocaine solution (1 mg/kg) and 0.01% clofelin (1 microgram/kg) was administered. Central hemodynamics, heart rhythm, external respiration function, uterine contractility, and fetal intrauterine status were assessed. The findings indicate that none of the methods had a negative impact on the vital parameters of women and newborns at any stage of anesthesia. However, a combination of epidural clofelin (1 microgram/kg) with lidocaine permits an appreciable decrease in the doses of both drugs without decreasing the efficacy of anesthesia. This method has a favorable effect on the course of labor: the mouth of the womb opens sooner at a lower uterine activity and there are no negative effects on the fetus and newborn.
|
Authors | A A Semenikhin, En Din Kim, S D Kurbanov |
Journal | Anesteziologiia i reanimatologiia
(Anesteziol Reanimatol)
1998 Sep-Oct
Issue 5
Pg. 51-4
ISSN: 0201-7563 [Print] Russia (Federation) |
Vernacular Title | Dlitel'naia épidural'naia analgeziia klofelinom v sochetanii s lidokainom pri obezbolivanii rodov. |
PMID | 9866250
(Publication Type: Comparative Study, English Abstract, Journal Article)
|
Chemical References |
- Analgesics
- Anesthetics, Local
- Lidocaine
- Clonidine
|
Topics |
- Adolescent
- Adult
- Analgesia, Epidural
- Analgesia, Obstetrical
- Analgesics
(administration & dosage)
- Anesthetics, Local
(administration & dosage)
- Clonidine
(administration & dosage)
- Drug Therapy, Combination
- Evaluation Studies as Topic
- Female
- Hemodynamics
- Humans
- Infant, Newborn
- Lidocaine
(administration & dosage)
- Respiration
- Time Factors
|