HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Prolonged epidural analgesia induced by clopheline in combination with lidocaine in obstetric analgesia].

Abstract
The study was carried out in 178 women without grave obstetrical or extragenital diseases. In group 1 labor pain was relieved by prolonged epidural anesthesia with 2% lidocaine solution (2-2.5 mg/kg), in group 2 prolonged epidural anesthesia with 1% lidocaine solution (1 mg/kg) and 0.01% clofelin (1 microgram/kg) was administered. Central hemodynamics, heart rhythm, external respiration function, uterine contractility, and fetal intrauterine status were assessed. The findings indicate that none of the methods had a negative impact on the vital parameters of women and newborns at any stage of anesthesia. However, a combination of epidural clofelin (1 microgram/kg) with lidocaine permits an appreciable decrease in the doses of both drugs without decreasing the efficacy of anesthesia. This method has a favorable effect on the course of labor: the mouth of the womb opens sooner at a lower uterine activity and there are no negative effects on the fetus and newborn.
AuthorsA A Semenikhin, En Din Kim, S D Kurbanov
JournalAnesteziologiia i reanimatologiia (Anesteziol Reanimatol) 1998 Sep-Oct Issue 5 Pg. 51-4 ISSN: 0201-7563 [Print] Russia (Federation)
Vernacular TitleDlitel'naia épidural'naia analgeziia klofelinom v sochetanii s lidokainom pri obezbolivanii rodov.
PMID9866250 (Publication Type: Comparative Study, English Abstract, Journal Article)
Chemical References
  • Analgesics
  • Anesthetics, Local
  • Lidocaine
  • Clonidine
Topics
  • Adolescent
  • Adult
  • Analgesia, Epidural
  • Analgesia, Obstetrical
  • Analgesics (administration & dosage)
  • Anesthetics, Local (administration & dosage)
  • Clonidine (administration & dosage)
  • Drug Therapy, Combination
  • Evaluation Studies as Topic
  • Female
  • Hemodynamics
  • Humans
  • Infant, Newborn
  • Lidocaine (administration & dosage)
  • Respiration
  • Time Factors

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: