Efficacy of clindamycin hydrochloride capsules for the treatment of deep pyoderma due to Staphylococcus intermedius infection in dogs.

Abstract

Clindamycin hydrochloride capsules (11 mg/kg body weight, q24 h) were administered orally to 20 dogs with deep staphylococcal pyoderma. Response to therapy was excellent in 100% of the dogs. Duration of therapy varied from 21 to 91 d, with an average duration of 45 d. Relapses occurred in 25% of the dogs within a 3-month period. One dog vomited when the clindamycin was given on an empty stomach. Under the conditions of the study, clindamycin was an effective, safe, and convenient antibiotic for the treatment of deep staphylococcal pyoderma in dogs.

• Authors: D W Scott, K E Beningo, W H Miller Jr, E Rothstein
• Journal: The Canadian veterinary journal = La revue veterinaire canadienne (Can Vet J) Vol. 39 Issue 12 Pg. 753-6 (Dec 1998) ISSN: 0008-5286 [Print] Canada
• PMID: 9861499 (Publication Type: Clinical Trial, Journal Article)

Chemical References

• Aminoglycosides
• Anti-Bacterial Agents
• Clindamycin

Topics

• Administration, Oral
• Aminoglycosides
• Animals
• Anti-Bacterial Agents (administration & dosage, therapeutic use)
• Clindamycin (administration & dosage, therapeutic use)
• Dog Diseases (drug therapy)
• Dogs
• Female
• Male
• Pyoderma (drug therapy, veterinary)
• Staphylococcal Infections (complications, drug therapy, veterinary)