Abstract | PURPOSE: METHODS: Twenty-eight posterior sub-Tenon's triamcinolone injections (40 mg) were given and the results analysed with a 6 month prospective follow-up in 13 cases. RESULTS: At 6 weeks follow-up, objective improvement in visual acuity occurred in 25 eyes (p < 0.05). Vitreous cellular activity was diminished in 21 eyes (p < 0.05). In most cases improvement was observed within 2 weeks of injection. No patient required repeat triamcinolone injection within 3 months and all patients previously treated with systemic immunosuppression were able to decrease or discontinue this treatment. Complications included transient elevation of intraocular pressure in 4 patients and persistent mild ptosis in 2 patients. CONCLUSIONS: We have demonstrated that posterior sub-Tenon's triamcinolone injection significantly decreases cystoid macular oedema, with a corresponding increase in visual acuity, in patients with posterior uveitis. Systemic immunosuppression may be reduced or discontinued with the avoidance of associated systemic side effects, and the technique has a high level of patient acceptability.
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Authors | V Tanner, J J Kanski, P A Frith |
Journal | Eye (London, England)
(Eye (Lond))
Vol. 12 ( Pt 4)
Pg. 679-85
( 1998)
ISSN: 0950-222X [Print] England |
PMID | 9850264
(Publication Type: Clinical Trial, Journal Article)
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Chemical References |
- Anti-Inflammatory Agents
- Glucocorticoids
- Triamcinolone
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Topics |
- Administration, Topical
- Adult
- Aged
- Anti-Inflammatory Agents
(administration & dosage)
- Female
- Follow-Up Studies
- Glucocorticoids
- Humans
- Injections, Intralesional
(methods)
- Male
- Middle Aged
- Prospective Studies
- Retrospective Studies
- Treatment Outcome
- Triamcinolone
(administration & dosage)
- Uveitis, Intermediate
(drug therapy)
- Uveitis, Posterior
(drug therapy)
- Visual Acuity
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