G-CSF: a very efficient therapy in chronic autoimmune neutropenia. A brief review of the literature.

Abstract

Autoimmune neutropenia (AIN) is a rare hematological disorder for which no standard treatment has been established so far. A brief review of the literature is presented herein concerning the use of G-CSF in this indication. The good results in terms of neutrophils increment and infection prophylaxis render G-CSF attractive for treating AIN. Hypotheses explaining its mechanisms of action are also discussed.

• Authors: F Bauduer
• Journal: Hematology and cell therapy (Hematol Cell Ther) Vol. 40 Issue 5 Pg. 189-91 (Oct 1998) ISSN: 1269-3286 [Print] France
• PMID: 9844813 (Publication Type: Journal Article, Review)

Chemical References

• Granulocyte Colony-Stimulating Factor

Topics

• Autoimmune Diseases (drug therapy, immunology)
• Chronic Disease
• Granulocyte Colony-Stimulating Factor (therapeutic use)
• Humans
• Neutropenia (drug therapy, immunology)
• Treatment Outcome