[A case of miliary tuberculosis with brain tuberculoma, following intraocular tuberculosis].

Abstract

A 52-year-old woman with visual loss of her left eye consulted a ophthalmology clinic. She was conducted left vitrectomy and administered corticosteroid under the diagnosis of uveitis of unknown cause. But her visual acuity was not improved. Although re-surgery was planned, pus retention was found in her left eye. After her left eye was resected, fever and general malaise appeared suddenly. Her chest X-ray film revealed diffuse micronodular opacities. Acid-fast bacilli were detected from her sputum and identified to be Mycobacterium tuberculosis. She was diagnosed miliary tuberculosis, and then antituberculous chemotherapy consisting of 4 drugs was started. Granulomatous inflammation destructing retina and numerous acid-fact bacilli were found in histologic examination of the resected eye. This case was thought to be miliary tuberculosis disseminated from intraocular tuberculosis. After 2 months of therapy, neurologic symptoms which might be caused by brain tuberucloma appeared and deteriorated rapidly. But by adding corticosteroid to antituberculous therapy, symptoms were diminished gradually.

• Authors: S Takakura, E Tanaka, T Kimoto, I Watanabe, H Matsumoto, K Tsuyuguchi, A Niimi, K Suzuki, R Amitani, F Kuze
• Journal: Kekkaku : [Tuberculosis] (Kekkaku) Vol. 73 Issue 10 Pg. 591-7 (Oct 1998) ISSN: 0022-9776 [Print] Japan
• PMID: 9844347 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Anti-Inflammatory Agents
• Antitubercular Agents
• Betamethasone

Topics

• Anti-Inflammatory Agents (administration & dosage)
• Antitubercular Agents (administration & dosage)
• Betamethasone (administration & dosage)
• Drug Therapy, Combination
• Female
• Humans
• Middle Aged
• Tuberculoma, Intracranial (drug therapy, etiology)
• Tuberculosis, Miliary (drug therapy, etiology)
• Tuberculosis, Ocular (complications, drug therapy)