Intermediate syndrome with delayed distal polyneuropathy from ethyl parathion poisoning.

Abstract

An acute poisoning in a 44-y-old female who ingested 50 ml of ethyl parathion concentrate (25 g) is described. She was treated by gastric lavage, administration of pralidoxime and atropine, and mechanical ventilation. As signs of intoxication disappeared at day 3, treatment was discontinued. The patient had a relapse of acute cholinergic crisis at day 4, and the same treatment was applied again. The acute poisoning phase was followed by an intermediate syndrome and delayed distal polyneuropathy. The clinical course of this severe ethyl parathion poisoning was favorable after 40 d.

• Authors: P Nisse, X Forceville, C Cezard, A Ameri, M Mathieu-Nolf
• Journal: Veterinary and human toxicology (Vet Hum Toxicol) Vol. 40 Issue 6 Pg. 349-52 (Dec 1998) ISSN: 0145-6296 [Print] United States
• PMID: 9830697 (Publication Type: Case Reports, Journal Article)

Chemical References

• Cholinesterase Reactivators
• Insecticides
• Pralidoxime Compounds
• Parathion
• Atropine
• pralidoxime

Topics

• Acute Disease
• Adult
• Atropine (therapeutic use)
• Cholinesterase Reactivators (therapeutic use)
• Drug Overdose (therapy)
• Drug Therapy, Combination
• Female
• Gastric Lavage
• Humans
• Insecticides (poisoning)
• Muscles (drug effects, pathology)
• Parathion (poisoning)
• Peripheral Nervous System Diseases (chemically induced, pathology)
• Pralidoxime Compounds (therapeutic use)
• Recurrence
• Respiration, Artificial
• Suicide, Attempted
• Syndrome
• Treatment Outcome